ISSN:
1432-1076
Keywords:
Muscle
;
Lipid storage myopathy
;
Carnitine
;
Morphometria
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract An 18-month-old boy presented with general hypotonia, decreased muscle strength, retarded motor development and stunted growth. The excretion of dicarboxylic acids was enhanced. EMG was normal. A muscle biopsy revealed a lipid storage myopathy. Oral daily supplementation with 2 g D,L-carnitine resulted in: (1) an increase of the growth velocity; (2) increased muscle strength, and (3) a decrease in the lipid fraction of the fibre volume. The carnitine content of the muscle biopsied prior to treatment appeared to be normal.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00441643
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