ISSN:
0170-2041
Keywords:
Thiophospholipids
;
Thioglycerol
;
Dithioglycerol
;
Phospholipids
;
Lipids
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Ether Analogues of Thio- and Dithiophospholipids with C-S-P BondThe efficient synthesis of 1-O-hexadecyl-2-O-methyl-3-thioglycero-3-phosphocholine (5a) and 1-S-hexadecyl-2-O-methyl-1,3-dithioglycero-3-phosphocholine (5b) based on phosphorylation of 1-O-hexadecyl-2-O-methyl-3-thioglycerol (3a) and 1-S-hexadecyl-2-O-methyl-1,3-dithioglycerol (3b) with 2-chloro-2-oxo-1,3,2-dioxaphospholane (6) followed by ring opening of the resulting intermediates 4a and 4b is described.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.1993199301216
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