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Genetic origin of diversity of human cytoskeletal tropomyosins (1987)

MacLeod, A. R.

New York, NY : Wiley-Blackwell

BioEssays 6 (1987), S. 208-212

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ISSN: 0265-9247

Keywords: Life and Medical Sciences ; Cell & Developmental Biology

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Biology , Medicine

Notes: Human fibroblasts express five tropomyosin-like proteins, three of which have been shown to be structurally related to each other and to tropomyoins from muscle sources. These cytoskeletal tropomyosins are transcribed from three separate, non-overlapping structural genes. However, each of these structural genes can also produce additional tropomyosin isoforms by a tissue-specific alternative mRNA splicing mechanism.

Additional Material: 4 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/bies.950060504

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