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  • 1
    Electronic Resource
    Electronic Resource
    Visual suppression from nondominant eye in the lateral geniculate nucleus: A comparison of cat and monkey (1979)
    Springer
    Experimental brain research 35 (1979), S. 465-477 
    Details
    ISSN: 1432-1106
    Keywords: Cat ; Monkey ; Lateral geniculate nucleus ; Visual nondominant suppression
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We have studied the suppression of firing in single LGN cells of cat and monkey in response to visual stimulation of the nondominant eye. In the cat LGN most of the cells of each of the main laminae show this nondominat suppression. X cells having their dominant input from the ipsilateral eye were suppressed to a significantly greater degree than any other cell type in the cat LGN. In the monkey LGN nondominant suppression was absent in all 19 X-like cells studied, whereas 6 of 21 Y-like cells showed nondominant suppression. Thus nondominant suppression is present in the magnocellular laminae of the monkey LGN, where the Y-like cells are found, but appears to be absent from the parvocellular laminae, where the X-like cells are found.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00236765
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The survival of neonatal rat retinal ganglion cells in vitro is enhanced in the presence of appropriate parts of the brain (1982)
    Springer
    Experimental brain research 48 (1982), S. 377-386 
    Details
    ISSN: 1432-1106
    Keywords: Retinal ganglion cells ; Cell death ; Trophic factors ; Tissue culture ; Development
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The enzyme horseradish peroxidase (HRP) was injected into the visual centres of the brains of neonatal rats. Following dissociation of retinae into tissue culture, the ganglion cells could be identified by appropriate histochemical staining for HRP reaction product. Cultures were prepared of dissociated retinae from rats aged 2–6 days postnatal. After 3 h the cultures were fixed, and HRP-labelled cells visualized and counted. Estimates were made of the number of ganglion cells per retina at each age. Results indicated a loss of ganglion cells during the first few postnatal days. This loss paralleled that observed in vivo. It was further found the retinal ganglion cells died rapidly in vitro when cultured in a minimal medium. Only 50% of ganglion cells originally plated remained viable after 24 h. However, the survival rate could be increased to 100% by coculturing the cells with diencephalon and mesencephalon; these contain the retinorecipient nuclei. Coculturing with cerebellum did not result in such an enhanced survival rate. Ganglion cells could be maintained over longer periods of time by reinoculating the cultures with additional tissue containing diencephalon and mesencephalon. These results support the hypothesis that developing neurons require trophic factors from their target tissues in order to survive.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00238614
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    Paper (German National Licenses)
    Fulltext
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