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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European archives of oto-rhino-laryngology and head & neck 245 (1988), S. 325-329 
    ISSN: 1434-4726
    Keywords: Cholesteatoma ; Terminal differentiation ; Transglutaminase ; Cell envelope
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The accumulation of desquamated keratinizing squamous epithelial cells appears to be a crucial factor in the pathogenesis of middle ear cholesteatomas. The accumulation of keratin debris is due to the proliferation and the terminal differentiation of basal keratinocytes. Since cholesteatomas are usually associated with inflammatory reactions in the middle ear cavity, we examined the effects of a granulation tissue conditioned medium on the terminal differentiation of basal keratinocytes in vitro. This conditioned medium stimulated the terminal differentiation of basal keratinocytes by showing: (a) increased incorporation of 3H-leucine into cell envelopes; (b) an increased number of SDS-insoluble cell envelopes; and (c) increased transglutaminase activity (as a marker for terminal cellular differentiation). Our present studies further suggest that inflammatory granulation tissue plays an important role in the clinical growth and development of the cholesteatoma.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    International journal of thermophysics 16 (1995), S. 33-43 
    ISSN: 1572-9567
    Keywords: free-standing film ; heat capacity ; layer-by-layer transition ; liquid crystal ; smectic-A hexatic-B transition
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Employing our free-standing film calorimetric system. we have identified three remarkable layer-by-layer transitions in several liquid crystal compounds. Each of these transitions can be well described by the simple power-law form:L = L 0 t. The layering transitions liMind near the smectic-A- hexatic-B and smectic-A crystal-B transitions are well characterized by the exponent v≈ 1 3. This value is consistent with models based on a van der Wads-like dominant intermolecular interaction. Another novel layer-by-layer thinning transition has been discovered above the hulk smectic-A isotropic transition of a perfluorinated liquid crystal compound. The value of the exponent obtained, v ≈ 3 4. cannot he easily explained using familiar models.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    International journal of thermophysics 15 (1994), S. 1189-1197 
    ISSN: 1572-9567
    Keywords: calorimeter ; density ; film ; heat capacity ; hexatic ; liquid crystal ; smectic-A-hexatic-B transition ; two-dimensional melting
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract A state-of-the-art calorimetric system has been established. The system enables us to measure simultaneously heat capacity and optical reflectivity of free-standing liquid-crystal films from many hundreds down to only two molecular layers in thickness. Our experimental results on the smectic-A-hexatic-B and smectic-C-smectic-I transitions cannot be described solely in terms of the creation of bond-orientational order, indicating that additional molecular order must be present in the hexatic phases of liquid crystals.
    Type of Medium: Electronic Resource
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