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  • Center/surround Interaction  (1)
  • Moving Slits  (1)
  • Strabismus  (1)
  • 1
    ISSN: 1432-1106
    Keywords: Key words Parvocellular neurons ; Lateral geniculate nucleus ; Strabismus ; Signal transfer ; Monkey
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  The effects of early discordant binocular vision on the fidelity of signal transfer in parvocellular neurons of the lateral geniculate nucleus (LGN) were investigated in rhesus monkeys reared with ocular misalignment (strabismus). Unilateral convergent strabismus (esotropia) was surgically induced in four infant monkeys between 20 and 30 days of age and the animals were reared in a normally lighted environment until they were adults. Extracellular microelectrode recordings were made in individual units of anesthetized and paralyzed subjects. Drifting sinusoidal gratings were used as visual stimuli. Within-unit comparisons of the LGN action potentials (LGN output) and S potentials (retinal input) were performed to determine the accuracy of signal transfer in the LGN. Contrary to the previous findings in the cat LGN, the signal transfer characteristics of parvocellular units in strabismic monkeys were normal regardless of stimulus spatial frequency, temporal frequency, or contrast. The differences between cats and monkeys in LGN circuitry and the relative maturity of the central visual pathway at the onset of strabismus may have contributed to the apparent species differences in the functional development of the LGN.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 43 (1981), S. 57-64 
    ISSN: 1432-1106
    Keywords: Siamese cat ; Optic Tract ; X and Y-retinal ganglion cells ; Moving Slits ; Response Properties ; Center/surround Interaction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The responses of X and Y-Type retinal ganglion cells in Siamese cats to moving slits were compared to those in common cats, in order to assess the center/surround interactions in Siamese cat receptive fields. Responses in the latter animal were quantitatively lower than those in common cats, the RF centers were larger, and the encounter rate for Y-type optic tract fibers was significantly lower than in common cats. Whereas response enhancement of common cat units was predictable following masking of the surround, such an effect could only be observed in Siamese cats when the contrast between the stimulus and background was increased considerably. These data suggest anomalous center/surround interactions in Siamese cats, probably due to the presence of weaker surround influences in that animal.
    Type of Medium: Electronic Resource
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