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  • 1
    Electronic Resource
    Electronic Resource
    Wertigkeit der Polymerase-Kettenreaktion (PCR) für die Diagnostik der tuberkulösen Meningitis (1998)
    Springer
    Der Nervenarzt 69 (1998), S. 502-506 
    Details
    ISSN: 1433-0407
    Keywords: Schlüsselwörter Tuberkulöse Meningitis ; Polymerase- Kettenreaktion ; Liquor ; Mycobacterium tuberculosis ; Mycobacterium fortuitum ; Key words Tuberculous meningitis ; Polymerase chain reaction ; Mycobacteria tuberculosis ; Mycobacteria fortuitum
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: , alsein ubiquitärer Keim mit geringer Pathogenität, Untersuchungsproben verunreinigen kann und die Verwendung von Primerpaaren, die gruppenspezifische mykobakterielle DNA erkennen, zu falsch-positiven Resultaten führen kann. Für die Validität der PCR ist daher neben der Sensitivität der Nachweisreaktion, die Spezifität der eingesetzten PCR-Primer von großer Bedeutung, um zwischen mykobakteriellen Subtypen zu differenzieren.
    Abstract: Value of the polymerase chain reaction (PCR) for diagnosing tuberculous meningitis
    Notes: Zusammenfassung
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001150050304
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  • 2
    Electronic Resource
    Electronic Resource
    Haemodilution with dextran 40 and hydroxyethyl starch and its effect on cerebral microcirculation (1989)
    Springer
    Journal of neurology 236 (1989), S. 164-167 
    Details
    ISSN: 1432-1459
    Keywords: Haemodilution ; Stroke therapy ; Cerebral blood flow ; Rheology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of haemodilution with Ringer's solution, hydroxyethyl starch (HAES) 200/0.5 10% and dextran 40 on cerebral blood flow (CBF) was measured in ten cats by means of the hydrogen clearance technique. As expected from theoretical considerations the haemodilution effect was short and not significant with Ringer's solution, but was 25% with HAES and 35% with dextrane 40. The corresponding rise in CBF was significant in both the latter but not with Ringer's solution. CBF was similarly highly correlated with diminution of haematocrit (Hct). The different effects of the substances on CBF could all be explained by their different effects on the Hct. Data analysis, together with recent literature, suggests that the dominating factor determining CBF was the O2-transport capacity, which in these experiments was in close relation to Hct. The results support the assumption that the increase of CBF by haemodilution is caused by a regulatory mechanism and not by a change of rheological parameters.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00314334
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    Paper (German National Licenses)
    Fulltext
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