ISSN:
1432-0533
Keywords:
Amyloid angiopathy
;
Cerebral hemorrhage
;
Elderly person
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract To investigate the relationship between cerebral amyloid angiopathy and subcortical (lobar) hemorrhage, we examined the severity of amyloid deposition in the leptomeningeal, cortical and subcortical arteries in 28 autopsied elderly patients with cerebral amyloid angiopathy with subcortical hemorrhage, deep cerebral hemorrhage or without hemorrhage. The severity was evaluated in terms of the frequency of amyloid-laden arteries and the degree of amyloid deposition within the arteries. The frequency of amyloid-laden arteries, especially among arteries over 200 μm in diameter, was higher in subcortical hemorrhage group than in the deep hemorrhage group and the non-hemorrhage group, and when the degree of amyloid deposition in the arteries was divided into four grades (none, mild, moderate or severe), the severity was higher in the subcortical hemorrhage group than in the deep cerebral hemorrhage group and the non-hemorrhage group. These results suggest that severe cerebral amyloid angiopathy is related to non-traumatic subcortical hemorrhage in elderly persons.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00228574
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