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Appendiceal tumors (1998)

Connor, S. J. ; Hanna, G. B. ; Frizelle, F. A.

Springer

Diseases of the colon & rectum 41 (1998), S. 75-80

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ISSN: 1530-0358

Keywords: Appendiceal tumors ; Carcinoid ; Appendicitis ; Colorectal cancer

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract BACKGROUND: Appendiceal tumors are rare and often unexpectedly discovered in an acute situation, in which decision-making is difficult. To help define the most appropriate management, a retrospective analysis was undertaken to describe the clinicopathologic behavior of appendiceal tumors, and the literature was reviewed of the management of the different types of appendiceal tumors. METHOD: From a single center, a histopathologic database of 7,970 appendectomies, all appendiceal tumors, were identified and case notes reviewed. Analysis of clinical presentation, histopathology, operation, and outcome is presented. RESULTS: During a 16-year period (7,970 appendectomies), 74 patients (0.9 percent) with appendiceal tumors were identified: 42 carcinoid, 12 benign, and 20 malignant. Acute appendicitis was the most common presentation (49 percent), and 9.5 percent were incidental findings. Primary malignant tumors of the appendix were found in 0.1 percent of all appendectomies. Secondary malignant disease was identified in the appendix of 11 patients, most commonly (55 percent) from patients with primary colorectal disease. There was a high incidence of synchronous and metachronous colorectal cancer in all appendiceal tumors: carcinoids, 10 percent; benign tumors, 33 percent; secondary malignancies, 55 percent; primary malignancies, 89 percent. CONCLUSION: Appendiceal tumors are uncommon and most often present as appendicitis. Most are benign and can be managed by appendectomy, except adenocarcinomas and carcinoids larger than 2 cm, which are most appropriately managed by right hemicolectomy. A suggested management algorithm is provided. Controversy exists over the management of carcinoids 1 to 2 cm in size and adenocarcinoids. All types of appendiceal tumors have a high incidence of synchronous and metachronous colorectal cancer.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF02236899

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Studies of poly(2,6-dimethyl-1,4-phenylene oxide blends): I. Copolymers of styrene and maleic anhydrideTaken in part from the M.S. Thesis of G. A. Hanna, University of Cincinnati, 1981. Portions of this work were presented at the Tenth North American Thermal Analysis Society Conference, Boston, Massachusetts, October 26-29, 1980 (Proceedings of the Tenth NATAS Conference, pp. 9-13) and the Michigan Macromolecualr Institute Symposium on “Polymer Compatibility and Incompatibility-Principles and Practices,” Midland, Michigan, August 17-22, 1980 (Polymer Compatibility and Incompatibility, K. Sole, ed., Harwood Academic Publishers, New york, Vol. 3 in the MMI Press Symposium Series, 1982). (1982)

Fried, J. R. ; Hanna, G. A.

Stamford, Conn. [u.a.] : Wiley-Blackwell

Polymer Engineering and Science 22 (1982), S. 705-718

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ISSN: 0032-3888

Keywords: Chemistry ; Chemical Engineering

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics

Notes: Blends of poly(2,6-dimethyl-l,4-phenylene oxide) and copolymers of styrene and maleic anhydride have been characterized by differential scanning calorimetry, dynamic mechanical analysis, and tensile measurements. Differential scanning calorimetry measurements indicate a single broadened glass transition for each blend of a 8 wt.% maleic anhydride copolymer, P(S-8MA), but two glass transitions when the copolymer composition is 14 wt.% MA, P(S-14MA). The glass transition temperatures of the former blends follow a sigmoidal dependence on blend composition, which is explained on the basis of evidence for phase separation from their dynamic mechanical tan 8 spectra. Tensile moduli of both blends reach a maximum at intermediate blend compositions; however, large-strain mechanical properties are highly dependent on blend compatibility and the method of sample preparation. The more homogeneous P(S-8MA) blends yield at low-to-intermediate copolymer compositions but fail in a brittle mode at higher compositions. All heterogeneous P(S-14MA) blends undergo brittle failure, but comparison of experimetal values of ultimate stress and strain with predictions from empirical relationships developed for composites indicate that interfacial adhesion is strong in these systems.

Additional Material: 28 Ill.