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  • 1
    Electronic Resource
    Electronic Resource
    Redistribution of cell membrane probes following contraction-induced injury of mouse soleus muscle (1995)
    Springer
    Cell & tissue research 282 (1995), S. 311-320 
    Details
    ISSN: 1432-0878
    Keywords: Key words: Cell membrane ; Fluorescent dyes ; Membrane permeability ; Plasmalemma ; Skeletal muscle ; T-tubules ; Mouse
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. Our aim was to study how mouse skeletal muscle membranes are altered by eccentric and isometric contractions. A fluorescent dialkyl carbocyanine dye (DiOC18(3)) was used to label muscle membranes, and the membranes accessible to the dye were observed by confocal laser scanning microscopy. Experiments were done on normal mouse soleus muscles and soleus muscles injured by 20 eccentric or 20 isometric contractions. Longitudinal optical sections of control muscle fibers revealed DiOC18(3) staining of the plasmalemma and regularly spaced transverse bands corresponding in location to the T-tubular system. Transverse optical sections showed an extensive reticular network with the DiOC18(3) staining. Injured muscle fibers showed distinctively different staining patterns in both longitudinal and transverse optical sections. Longitudinal optical sections of the injured fibers revealed staining in a longitudinally-oriented pattern. No correlations were found between the abnormal DiOC18(3) staining and the reductions in maximal isometric tetanic force or release of lactate dehydrogenase (P≥0.32). Additionally, no difference in the extent of abnormal staining was found between muscles performing eccentric contractions and those performing the less damaging isometric contractions. However, many fibers in muscles injured by eccentric contractions showed swollen regions with marked loss of membrane integrity and an elevated free cytosolic calcium concentration as observed in Fluo-3 images. In conclusion, a loss of cell membrane integrity results from contractile activity, enabling DiOC18(3) staining of internal membranes. The resulting staining pattern is striking and fibers with damaged cell membranes are easily distinguished from uninjured ones.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004410050482
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Redistribution of cell membrane probes following contraction-induced injury of mouse soleus muscle (1995)
    Springer
    Cell & tissue research 282 (1995), S. 311-320 
    Details
    ISSN: 1432-0878
    Keywords: Cell membrane ; Fluorescent dyes ; Membrane permeability ; Plasmalemma ; Skeletal muscle ; T-tubules ; Mouse
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Our aim was to study how mouse skeletal muscle membranes are altered by eccentric and isometric contractions. A fluorescent dialkyl carbocyanine dye (DiOC18(3)) was used to label muscle membranes, and the membranes accessible to the dye were observed by confocal laser scanning microscopy. Experiments were done on normal mouse soleus muscles and soleus muscles injured by 20 eccentric or 20 isometric contractions. Longitudinal optical sections of control muscle fibers revealed DiOC18(3) staining of the plasmalemma and regularly spaced transverse bands corresponding in location to the T-tubular system. Transverse optical sections showed an extensive reticular network with the DiOC18(3) staining. Injured muscle fibers showed distinctively different staining patterns in both longitudinal and transverse optical sections. Longitudinal optical sections of the injured fibers revealed staining in a longitudinally-oriented pattern. No correlations were found between the abnormal DiOC18(3) staining and the reductions in maximal isometric tetanic force or release of lactate dehydrogenase (P≥0.32). Additionally, no difference in the extent of abnormal staining was found between muscles performing eccentric contractions and those performing the less damaging isometric contractions. However, many fibers in muscles injured by eccentric contractions showed swollen regions with marked loss of membrane integrity and an elevated free cytosolic calcium concentration as observed in Fluo-3 images. In conclusion, a loss of cell membrane integrity results from contractile activity, enabling DiOC18(3) staining of internal membranes. The resulting staining pattern is striking and fibers with damaged cell membranes are easily distinguished from uninjured ones.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00319121
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Dynamics of polymeric liquids. Volume 2: Kinetic Theory By R. Ryron Bird, Charles F. Curtis, Robert C. Armstrong, and Ole Hassager, John Wiley & Sons, Inc., New York, 2nd Ed., 1987, 437 + xxi pp. (1989)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 35 (1989), S. 1399-1402 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690350823
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Non-isothermal channel flow of non-Newtonian fluids with viscous heating (1982)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 28 (1982), S. 294-301 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Approximate analytical solutions of the local temperature variations, due to viscous heating, in channel flows of non-Newtonian fluids with small Nahme-Griffith numbers were obtained by the WKB-J method. The results are general and easy to use so that extensive numerical computations are not required. Comparisons between the approximate analytical solution and complete numerical solution showed that the relative differences were very small.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690280219
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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