ISSN:
1435-1536
Keywords:
Helix-coil transition
;
poly(hydroxyalkyl-L-glutamine)
;
poly{bis(hydroxyethyl)-L-glutamine}
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
Abstract Circular dichroism spectra are reported for poly {bis(hydroxyethyl)-L-glutamine}. Its conformation is predominantly that of a statistical coil at or above ambient temperature in water. It becomes partially helical upon cooling. The helix-forming potential of this polypeptide in water is between that of poly(hydroxyethyl-L-glutamine) and poly(hydroxypropyl-L-glutamine). The polypeptide has a large helix content when the solvent is rich in trifluoroethanol.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01421998
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