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  • 1
    Electronic Resource
    Electronic Resource
    A Ras protein from a phytopathogenic fungus causes defects in hyphal growth polarity, and induces tumors in mice (1999)
    Springer
    Molecular genetics and genomics 262 (1999), S. 46-54 
    Details
    ISSN: 1617-4623
    Keywords: Key wordsColletotrichum trifolii ; Growth polarity ; Ras ; Signal transduction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Ras is a low-molecular-weight guanine nucleotide (GDP/GTP)-binding protein that transduces signals for growth and differentiation in eukaryotes. In mammals, the importance of Ras in regulating growth is underscored by the observation that activating mutations in ras genes are found in many animal tumors. Colletotrichum trifolii is a filamentous fungal pathogen of alfalfa which causes anthracnose disease. To investigate signaling pathways that regulate growth and development in this fungus, a gene encoding a Ras homolog (CT-Ras) was cloned from C. trifolii. CT-Ras exhibited extensive amino acid similarity to Ras proteins from higher and lower eukaryotes. A single amino acid change resulting in mutationally activated CT-Ras induced cellular transformation of mouse (NIH 3T3) fibroblasts and tumor formation in nu/nu mice. In Colletotrichum, mutationally activated CT-Ras induced abnormal hyphal proliferation and defects in polarized growth, and significantly reduced differentiation in a nutrient-dependent manner. These results show that C. trifolii Ras is a functional growth regulator in both mammals and fungi, and demonstrate that proper regulation of Ras is required for normal fungal growth and development.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004380051058
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  • 2
    Electronic Resource
    Electronic Resource
    The relationship between the equilibrium melting temperature and the supermolecular structure of several polyoxetanes and polyethylene oxide (1987)
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 27 (1987), S. 781-787 
    Details
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The relationships between equilibrium melting temperatures (Tm*) and crystalline morphology of poly[3,3bis(ethoxymethyl)oxetane], (polyBEMO), poly[3,3-bis (azidomethyl)oxetane], (polyBAMO), and poly(ethylene oxide), (PEO), were characterized. The Hoffman-Weeks extrapolation procedure led to Tm* values of 92, 102, and 69°C for these three polymers, respectively. The gross morphologies of polyBEMO, polyBAMO, and PEO were studied as a function of melt-liquid temperature (Ti) and isothermal crystallization temperature (Tc) by visible light microscopy. Spherulitic morphologies were observed for polyBEMO, polyBAMO, and PEO when Ti was above Tm*, while nonspherulitic (hedritic) morphologies were observed at Tls below Tm*. Mixed morphologies were observed when Tl was approximately equal to Tm*.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pen.760271103
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Über die selektive Absorption von Ketonen (1914)
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 47 (1914), S. 876-887 
    Details
    ISSN: 0365-9496
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 5 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cber.191404701140
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    Paper (German National Licenses)
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