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Choroid Plexus Carcinoma in Infants: Report of Two Cases and Review of the Literature (1998)

Shinoda, J. ; Kawaguchi, M. ; Matsuhisa, T. ; [et al.]

Springer

Acta neurochirurgica 140 (1998), S. 557-563

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ISSN: 0942-0940

Keywords: Keywords: Choroid plexus carcinoma; infant; surgery; chemotherapy; radiotherapy.

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary Choroid plexus carcinoma (CPC) is a rare malignant brain tumour which occurs predominantly in childhood. We present the cases of two infants with CPC. One, a 6-month-old boy with the tumour in the right lateral ventricle, who died of a postoperative intracranial haemorrhage and severe gastrointestinal bleeding, and the other, a 9-month-old boy with the tumour in the fourth ventricle, who has been well without recurrence for 12 months after total removal in combination with chemotherapy using cisplatin and VP-16 and local radiotherapy. In the 54 CPC cases in children under 2 years of age including our 2 cases in which the clinical results were described in the literature since 1983, tumour location (lateral ventricle, p=0.0225), surgery (gross total resection, p=0.0447), and chemotherapy (yes, p=0.0010) were revealed to be significant positive prognostic factors by the univariate analysis using the log rank test, and surgery (gross total removal, p=0.0259) and chemotherapy (yes, p=0.0016) were independent, significant positive prognostic factors in the multivariate analysis using the Cox proportional hazard regression model. Although there is a risk in doing a statistical analysis of other people's reports, these results suggest that, at present, the gross total removal of the tumour with intensive chemotherapy is the best choice of initial treatment for young children with CPC, and that radiotherapy should be considered for patients after 24 months of age and/or should be performed locally.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/s007010050140

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Permeability of water and water vapor through cellulosic membranes (1975)

Kawaguchi, M. ; Taniguchi, T. ; Tochigi, K. ; [et al.]

New York, NY [u.a.] : Wiley-Blackwell

Journal of Applied Polymer Science 19 (1975), S. 2515-2527

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ISSN: 0021-8995

Keywords: Chemistry ; Polymer and Materials Science

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics

Notes: To elucidate the water transport mechanism through homogeneous membranes, water and water vapor permeation through crosslinked cellulose membranes, cellulose diacetate, and cellulose triacetate membranes are studied. It is found that the water flux increases with the degree of hydration; and as for cellulose membranes, the degree of hydration is an increasing function of the degree of crosslinking. Activation energy of hydraulic permeability (Kw) is not equal to that of purely viscous flow, and is smaller than that of the water vapor diffusion coefficient (D̄) for all membranes. The free-volume concept relating the molar frictional coefficient to temperature and to degree of hydration explains reasonably the temperature dependence of hydraulic permeability and of water vapor diffusion coefficient and gives adequate values for the fractional free volume of the system. The critical volume V*, appearing in the Cohen-Turnbull expression between friction coefficient and free volume fraction, may be considered as the size of the cluster of water molecules. The value of V* in the case of hydraulic permeability is larger than that for water vapor diffusion by several times. Furthermore, the value V* increases with increase of degree of hydration for water permeation and water vapor diffusion.

Additional Material: 15 Ill.