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  • 1
    Electronic Resource
    Electronic Resource
    Cell properties in the medial interlaminar nucleus of the cat's lateral geniculate complex in relation to the transient/sustained classification (1975)
    Springer
    Experimental brain research 22 (1975), S. 327-329 
    Details
    ISSN: 1432-1106
    Keywords: Lateral geniculate nucleus ; Medial interlaminar nucleus ; Receptive field properties ; Transient/sustained classification
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00234773
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  • 2
    Electronic Resource
    Electronic Resource
    Responses of cells in the dorsal lateral geniculate complex of the cat to textured visual stimuli (1976)
    Springer
    Experimental brain research 25 (1976), S. 323-326 
    Details
    ISSN: 1432-1106
    Keywords: Lateral geniculate nucleus ; Medial interlaminar nucleus ; Receptive field ; ‘Visual noise’
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00234022
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Tumour steroid hormone synthesis and estrogen receptor status in breast cancer patients (1981)
    Springer
    Breast cancer research and treatment 1 (1981), S. 263-266 
    Details
    ISSN: 1573-7217
    Keywords: breast cancer ; estrogen receptors ; steroid biosynthesis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The capacity of breast cancer to synthesise active androgens and estrogens has been related to estrogen receptor (ER) status in 79 postmenopausal patients with breast cancer. Although there was no quantitative relationship between levels of ER and steroid metabolism in ER positive tumours, there was (a) a positive correlation between estrogen synthesis and ER positivity and (b) increased androgen synthesis and ER negativity. This may imply an inherent difference in the handling of hormones in ER positive and negative tumours.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01806266
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Fragment pathway analysis using automated tandem mass spectrometry on an ion-trap mass spectrometer (1990)
    New York, NY : Wiley-Blackwell
    Rapid Communications in Mass Spectrometry 4 (1990), S. 103-107 
    Details
    ISSN: 0951-4198
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: A “key-sequence” procedure is presented for the automated tandem mass spectrometric analysis of compounds on a Finnigan ion-trap mass spectrometer. This allows fragmentation pathways of a range of masses or even a complete spectrum to be prepared automatically, obviating the tiresome preparation and optimization of individual scan-editor files. The procedure is limited by the speed of the driving computer; an “IBM-AT”, for example, permits more than 10 mass units to be scanned per minute. It is calibrated with perfluorotributylamine and methyl stearate is used to demonstrate its results. The Finnigan ion-trap “programming option” is necessary for implementation of the procedure.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/rcm.1290040403
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  • 5
    Electronic Resource
    Electronic Resource
    Studies on immobilized papain (1973)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 15 (1973), S. 455-466 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Papain was covalently coupled to ZrO2-coated porous glass by several different methods. These derivatives were characterized and their operational half-lives determined using casein substrate. Papain covalently coupled to the porous glass, previously converted to a carboxylic acid derivative, through amide linkage gave a 35 day operational half-life.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260150303
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  • 6
    Electronic Resource
    Electronic Resource
    Protease covalently coupled to porous glass: Preparation and characterization (1975)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 17 (1975), S. 1019-1027 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A microbial protease was immobilized by covalent attachment, to porous glass. This material was characterized for pH optimum, thermal stability, and operational half-life using casein as substrate.The immobilized enzyme was used for preparation of soya hydrolysates, low in free amino acids with high solubility.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260170706
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  • 7
    Electronic Resource
    Electronic Resource
    Invertase covalently coupled to porous glass: Preparation and characterization (1972)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 14 (1972), S. 637-645 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The enzyme invertase has been covalently coupled to porous glass particles. The product is extremely stable over a long period of time. Kinetic values for the immobilized enzyme are similar to the native enzyme. Excellent enzymatic activity for the immobilized enzyme was exhibited over a broad pH range. The immobilized enzyme when continuously operated for one month was found to have an operational half-life of over 40 days.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260140409
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  • 8
    Electronic Resource
    Electronic Resource
    Protein hydrolysis with immobilized enzymes (1975)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 17 (1975), S. 451-453 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260170314
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  • 9
    Electronic Resource
    Electronic Resource
    Effects of drugs associated with hyperprolactinemia on plasma steroids and on steroid receptors and metabolism in human breast cancer (1983)
    Springer
    Breast cancer research and treatment 3 (1983), S. 331-338 
    Details
    ISSN: 1573-7217
    Keywords: breast cancer ; estrogen receptor ; hyperprolactinemic drugs ; prolactin ; steroid biosynthesis ; steroid hormones
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Certain commonly taken pharmaceutical preparations induce increased levels of plasma prolactin. The effects of these drugs on (a) tumor steroid receptors and metabolism, and (b) plasma hormones and hormone binding proteins have been studied in postmenopausal women with breast cancer. Two groups have been compared, 18 patients on drug treatment for at least 2 months and 15 subjects with no history of drug ingestion. Patients taking medication had significantly higher levels of plasma prolactin compared with control women. No significant difference was observed between the groups with regard to the plasma concentrations of dehydroepiandrosterone (DHA) and its sulphate (DHS), testosterone, estrone, estradiol-17β, sex hormone binding globulin (SHBG), and albumin. Similarly, no difference was observed between these two groups with regard to estrogen receptor (ER), progestogen receptor (PR), or androgen receptor (AR) levels in the tumors nor their ability to metabolize (7−3H) testosterone. It is considered that the ingestion of these drugs does not affect tumor mechanisms involving steroids.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01807585
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    Paper (German National Licenses)
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  • 10
    Electronic Resource
    Electronic Resource
    An in vitro test system for estimation of blood compatibility of biomaterials (1974)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 8 (1974), S. 341-356 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: An in vitro test cell is described which permits exposure of artificial surfaces in sheet or film form to native human blood in the absence of a blood-air interface. Evaluation of Cuprophane, polyethylene, Silastic, and silicone-coated glass in the in vitro cell showed Cuprophane and silicone-coated glass to produce the least activation of the intrinsic coagulation system, while Silastic produced the greatest degree of activation. Polyethylene gave results intermediate between those obtained with the other materials. Each of these four different materials was evaluated in the elliptical cell test system multiple times with blood from 13 different donors.Our data suggest that with the present test system and the proper experimental design, one might expect that, “on the average,” performance of 36 tests on each of two materials will be sufficient for a 10% difference in their compatibility with blood to be statistically significant at the 5% level. The number of tests is 26 for significance at the 10% level.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820080602
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