ISSN:
0749-1581
Keywords:
β-Phenylaspartic acids
;
Configurational assignment
;
1H and 13C NMR
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Vicinal 3J(HH) and 3J(13CH) coupling constants are reported for the two diastereoisomers of β-phenylaspartic acid at various pH values. A comparison between these coupling constants and those expected from the possible conformations of these molecules allows configurational assignments to be made. In strong acidic medium we observed intermediate values for 3J(HH) for both isomers, for one isomer two intermediate values for 3J(Co-α, H-β) and 3J(Co-β, H-α), and for the other isomer a very small value for 3J(CO-α, H-β) and an intermediate value for 3J(Co-β, H-α). The discussion shows that the former has the RR/SS configuration and the latter the RS/SR configuration.
Additional Material:
3 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mrc.1260260809
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