ISSN:
0377-0486
Keywords:
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
,
Physics
Notes:
A Raman and infrared investigation of SOAz 2, one of the two allotropic varieties of a new anticancer agent, SOAz, has been made in order to have a better understanding of its interactions with DNA. A third allotropic variety, named SOAz 3, was found to be produced when heating SOAz 2. The SOAz 3 → SOAz 2 transformation is also described. SOAz 3 appears to be the conformation of SOAz in aqueous solution and consequently seems to be the moiety which is responsible for its anticancer effectiveness.
Additional Material:
7 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jrs.1250130109
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