ISSN:
0941-1216
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The present account deals with the synthesis, stereochemistry and biological properties of coordinatively saturated difluoroboron(III) compounds. The ligands used during the present investigations were prepared by the condensation of [1-(thien-2-yl)-ethanone], [1-(pyridin-2-yl)ethanone], [1-(furan-2-yl)ethanone], [1-(naphthen-2-yl)ethanone] and [(thien-2-yl)methanal] with 2-mercapto-aniline. The unimolar reactions between borontrifluoride-acetic acid and these ligands have produced BF2(NS) type of biologically active complexes. The quantitative and spectral analyses comprising u.v., i.r. and n.m.r. (1H, 11B, 13C and 19F) helped in establishing the structures of the resulting complexes. In the quest for better fungicides and bactericides, studies were conducted to assess the growth inhibiting potential of the synthesized complexes against various fungal and bacterial strains. The studies demonstrate that the concentration reached levels which are sufficient to inhibit and kill the pathogens.
Additional Material:
7 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/prac.19943360815
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