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  • 1
    Digitale Medien
    Digitale Medien
    Characterization of the chromatin structure in the upstream region of the chicken alpha-globin gene domain (1994)
    Springer
    Molecular genetics and genomics 242 (1994), S. 649-652 
    Details
    ISSN: 1617-4623
    Schlagwort(e): α-Globin domain ; Hypersensitive sites ; Locus control region ; Chromatin structure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract The distribution of DNase I hypersensitive sites upstream of the chicken α-globin gene cluster was studied. A group of hypersensitive sites with a complex pattern of tissue specificity, including erythroid-specific elements, was found at a distance of 11.5–14.5 kb upstream of the π gene, the first gene in the cluster. The observations indicate that this area, located upstream of the block of AT-rich sequences and MAR sites (at −8 kb) and upstream of the site of permanent DNA attachment to the nuclear matrix (−3 kb), still belongs to the domain of the α-globin genes.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00283418
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    The sequence-specific nuclear matrix binding factor F6 is a chicken GATA-like protein (1993)
    Springer
    Molecular genetics and genomics 238 (1993), S. 309-314 
    Details
    ISSN: 1617-4623
    Schlagwort(e): Nuclear matrix attachment ; GATA ; Chicken globin genes ; DNA-binding protein
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract The sequence-specific DNA-binding protein factor F6, which binds upstream of the cluster of the chicken α-globin genes, has previously been found to interact with a DNA fragment containing a replication origin and a nuclear matrix binding site. This protein has been partially characterized. Based on its molecular weight and binding affinity, F6 belongs to a family of GATA proteins, the chicken equivalent of transcription factor NFE-1. An oligonucleotide including the binding site for F6 competes for binding of the above-mentioned DNA fragment to the nuclear matrix. This indicates an involvement of this protein in the interaction between DNA and the nuclear matrix.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00291988
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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    Artikel (Nationallizenzen)
    Volltext
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