ISSN:
1573-7284
Keywords:
Chloramphenicol resistance
;
Drug resistance
;
Streptococcus pneumoniae
;
Staphylococcus aureus
;
Streptococcal genetics
;
Transformation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Southern blot hybridization and pneumococcal transformation were used to study the epidemiology at a molecular level of the genes for chloramphenicol resistance (cat) in streptococci and staphylococci. The cat gene of staphylococcal plasmid pC194 showed homology to the cat genes of the chromosomal elements of 5 different strains of Streptococcus pneumoniae and of Streptococcus agalactiae B109. DNA sequence homology was also detected between the cat gene of staphylococcal plasmid pC221 and the cat gene of broad host range conjugative plasmid pIP501, originally isolated from S. agalactiae. Two different cat genes appear to be present in clinical isolates of both streptococci and staphylococci.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00152687
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