ISSN:
1432-2072
Keywords:
Comparative behaviour
;
(+)-Methamphetamine
;
(+)-Amphetamine
;
Chronic administration
;
Mouse
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The behavioural effects induced in mice by the chronic administration of (+)-methamphetamine (MA) and (+)-amphetamine (A) at three dosages were studied under identical research conditions. The results indicated that MA exerted greater central excitation than A. At the dosage 0.64 mg/kg quiescence was decreased and activity increased more by MA than A. Hyperactivity induced at the 2.5 mg/kg dosage was sustained over a longer time period with MA. Frenzied self-tearing emerged with repeated drug administration at the 10 mg/kg dose in more MA-treated than A-treated animals.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00431729
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