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  • Chronic bronchiolitis  (1)
  • Key words Respiratory syncytial virus  (1)
  • Knorpelersatz  (1)
  • 1
    ISSN: 1432-2307
    Keywords: Key words Respiratory syncytial virus ; RSV ; Chronic bronchiolitis ; RSV persistence
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Human (RSV) and bovine (BRSV) respiratory syncytial virus cause similar infections of the lower respiratory tract. Therefore, experimentally infected calves are suited to the study of RSV-induced chronic bronchiolitis. Colostrum-fed calves aged 17–24 days were successfully infected with BRSV. BRSV strain 375 was applied as an aerosol on 4 consecutive days. Clinical symptoms were already evident on the 1st day after infection. The calves were necropsied 12 weeks after the first infection. Focal severe chronic bronchiolitis with atelectasis and focal bronchiolitis obliterans were demonstrated. The bronchiolar lumina were filled with secretion. Transmission electron microscopy revealed an alteration of the ciliogenesis and partial loss of cilia. Immunhistochemically virus P protein could still be detected, mainly in the epithelial cells of the inflamed bronchioli.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1434-3924
    Keywords: Schlüsselwörter Gonarthrose ; Chondromalazie ; Debridement ; Knorpelersatz ; Key words Degenerative gonarthritis ; Chondromalacia ; Debridement ; Cartilage restoration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Treatment of degenerative gonarthritis is one of the main fields of arthroscopy. Different treatment possibilities are discussed considering recent literature, especially concerning dependence of indication on degree of chondromalacia, success and structural changes. Experimental stability testing shows increased translation in gonarthritis as a sign of instability. Partial resection of the posterior meniscal horns lead to considerable loss of stability, causing cartilage defects if no muscular compensation takes place. Finally, treatment methods for cartilage restoration are compared.
    Notes: Die Behandlung der Gonarthrose ist eines der Hauptarbeitsfelder der Arthroskopie. Die verschiedenen Verfahren werden unter Berücksichtigung der aktuellen Literatur abgewogen, insbesondere hinsichtlich ihrer vom Grad der Chondromalazie abhängigen Indikation, der Erfolgsaussichten und der strukturellen Gewebsveränderungen. Experimentelle Stabilitätstestungen zeigen die bei Gonarthrose vorliegende vermehrte Translation als Instabilitätszeichen. Meniskushinterhornteilresektionen erweisen sich als erhebliche Reduktion der sekundären Stabilisation, was ohne muskuläre Kompensation zu erheblichen Knorpeldefekten führt. Schließlich werden Verfahren der Knorpelrestauration verglichen.
    Type of Medium: Electronic Resource
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