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Psychological profile of women with chronic pelvic pain (1986)

Magni, G. ; Andreoli, C. ; Leo, D. ; [et al.]

Springer

Archives of gynecology and obstetrics 237 (1986), S. 165-168

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ISSN: 1432-0711

Keywords: Middlesex Hospital Questionnaire ; Zung SDS ; Chronic pelvic pain ; Organic ; Idiopathic ; Depression

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary Using the Middlesex Hospital Questionnaire (MHQ) and the Zung Self-Rating Depression Scale (SDS) psychological distress was measured in 30 women who underwent laparoscopy for chronic pelvic pain and in 30 matched controls. Both organic pelvic pain patients (OPPs) and idiopathic pelvic pain patients (IPPs) reported higher scores for somatisation than controls. IPPs scored higher than OPPs and controls on the Zung SDS, while no difference emerged in this scale between OPPs and controls. No correlations were found between age or duration of symptoms and somatisation and depression scores. On the basis of the above reported results the authors suggest that some forms of idiopathic chronic pelvic pain might represent an expression of a depressive disorder.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF02133860

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Origin and nature of spontaneous mutations in meiotic organisms (1964)

Magni, G. E.

Philadelphia : Wiley-Blackwell

Journal of Cellular and Comparative Physiology 64 (1964), S. 165-171

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ISSN: 0095-9898

Keywords: Life and Medical Sciences ; Cell & Developmental Biology

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Biology , Medicine

Notes: Spontaneous reversion rates of biochemical mutants in cells of Saccharomyces cerevisiae undergoing meiosis are several times higher than those of cells mitotically reproducing. It has been demonstrated that the great majority of revertants occurring during a meiotic process are associated with chromosomal exchanges in the region of the specific locus. This leads to the hypothesis that during meiosis back mutations occur as a consequence of unequal crossing-over causing base losses or insertions in the DNA and, therefore, restroration of a sequence compatible with the synthesis of functioning proteins. The same phenomenon holds true also for forward mutations. Preliminary experiments show that, as expected, mutations due to base substitutions do not revert in meiosis at a rate higher than in mitosis. Exchange-associated mutations seem to occur also in other organisms such as bacteriophages, bacteria, Neurospora, and Drosophila.

Additional Material: 2 Tab.