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  • Circular dichroism spectroscopy  (1)
  • Cyclodextrin additives  (1)
  • IGFBPs  (1)
  • Key words. Hamiltonian systems, resonant invariant tori, KAM-type theorem  (1)
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Material
Years
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Conformational analysis of synthetic peptides encompassing the factor XI and prekallikrein overlapping binding domains of high molecular weight kininogen
    Amsterdam : Elsevier
    Peptides 14 (1993), S. 867-876 
    Details
    ISSN: 0196-9781
    Keywords: Circular dichroism spectroscopy ; Factor XI ; Fluorescence spectroscopy ; Kininogen ; Peptide conformation ; Prekallikrein ; Protein conformation ; Titration calorimetry
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0196-9781(93)90061-K
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    KAM-Type Theorem on Resonant Surfaces for Nearly Integrable Hamiltonian Systems (2000)
    Springer
    Journal of nonlinear science 10 (2000), S. 49-68 
    Details
    ISSN: 1432-1467
    Keywords: Key words. Hamiltonian systems, resonant invariant tori, KAM-type theorem
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Physics
    Notes: Summary. In this paper, we consider analytic perturbations of an integrable Hamiltonian system in a given resonant surface. It is proved that, for most frequencies on the resonant surface, the resonant torus foliated by nonresonant lower dimensional tori is not destroyed completely and that there are some lower dimensional tori which survive the perturbation if the Hamiltonian satisfies a certain nondegenerate condition. The surviving tori might be elliptic, hyperbolic, or of mixed type. This shows that there are many orbits in the resonant zone which are regular as in the case of integrable systems. This behavior might serve as an obstacle to Arnold diffusion. The persistence of hyperbolic lower dimensional tori has been considered by many authors [5], [6], [15], [16], mainly for multiplicity one resonant case. To deal with the mechanisms of the destruction of the resonant tori of higher multiplicity into nonhyperbolic lower dimensional tori, we have to deal with some small coefficient matrices that are the generalization of small divisors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003329910003
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Differential effects of thermal injury on circulating insulin-like growth factor binding proteins in burn patients (1994)
    Springer
    Molecular and cellular biochemistry 135 (1994), S. 171-180 
    Details
    ISSN: 1573-4919
    Keywords: IGF-1 ; IGFBPs ; burn ; serum
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract The results of this report provide evidence that insulin-like growth factor-1 binding proteins (IGFBPs) in human sera are differentially regulated as a result of severe burn injury. Using the ligand binding technique,125I-IGF-1 visualizes 5 different protein bands corresponding to those previously reported for IGFBP-1 to 4 with apparent sizes of 23–42 kd in serum samples prepared from severely burned patients and healthy individuals. The level of IGFBP-3 was significantly decreased within 3–5 days of injury and remained depressed for up to 20 days post injury. The average level of this binding protein reached its lowest value within 3–5 days of the injury (3.8±1.48% relative to day 0–1 value, n=4, p〈0.001). Serum samples from 3 to 4 patients showed no recovery within 20 days post injury and the level of IGFBP-3 remained significantly depressed (p〈0.01). In contrast, the levels of IGFBP-2 and IGFBP-4 increased 2 and 3 fold in the same serum samples within 3–5 days of the burn injury, respectively. This increase returns to normal (day 0–1 value) within 7–10 days for IGFBP-2, but the level of IGFBP-4 remained elevated 4 fold relative to the day 0–1 (p〈0.01). However, the abundance of IGFBP-1 in these serum samples was not significantly altered by the burn injury. By controlling for protein loading, these apparent alterations of IGFBPs in the sera of burned patients were not due to hemodilution. Similarly, significant reductions in IGFBP-3 were not likely due to IGFBP-3 specific protease activity in the sera of burn patients since incubation of sera from burn patients and normal individuals at 37° C did not alter the pattern of IGFBPs in sera obtained from normal individuals. Of interest, the level of IGF-1 protein in these samples was also markedly reduced following severe burn injury similar to IGFBP-3. The results of this study suggest that a marked reduction of serum IGF-1 seen in burn patients is associated with a significant reduction of IGFBP-3, a major IGF-1 binding protein in human serum.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00926520
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Study of the chromatographic behavior and inclusion constants of new fluorescence agents by use of cyclodextrin additives under conditions of steady- and dynamic-state equilibrium and with fluorescence detection (1999)
    Springer
    Chromatographia 49 (1999), S. 95-104 
    Details
    ISSN: 1612-1112
    Keywords: Column liquid chromatography ; Cyclodextrin additives ; Fluorescence agents
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary We report four new derivatization agents, acridone-N-acetic acid (ARC), carbazole-9-ylacetic acid (CRA), carbazole-9-ylpropionic acid (CRP), and 2-methyl-2-carbazole-9-ylacetic acid (MCRA), with strong fluorescence emission which has low dependence on solvent polarity. The emission maxima for ARC, CRA, CRP, and MCRA were 430 nm (λex 404 nm), 368 nm (λex 335 nm), 356 nm (λex 340 nm) and 360 nm (λex 330 nm), respectively. The effects of mobile-phase composition, pH, and temperature on the liquid chromatographic retention behavior of the four fluorescence agents were investigated. An experimental model was established for calculating the inclusion constants of cyclodextrin (CD) complexes in the dynamic state, using β-cyclodextrin (β-CD) and hydroxypropyl-β-cyclodextrin (HP-β-CD) as examples, and different mobilephase compositions. On the basis of the model, the inclusion constants of the solutes in pure water (K fw) were determined by extrapolation. The thermodynamic parameters (ΔH o and ΔS o) and dissociation constantsK am for the solutes in this chromatographic system were obtained by means of capacity factor (k) values using a corresponding model formulation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02467195
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    Paper (German National Licenses)
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