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Preliminary studies of clonidine in psychotic patients (1988)

Angrist, B. ; Smith, M. ; Adler, L. ; [et al.]

Springer

Journal of neural transmission 71 (1988), S. 115-121

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ISSN: 1435-1463

Keywords: Clonidine ; psychosis ; norepinephrine ; norepinephrine-dopamine interaction

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary Twelve psychotic patients received a mean dose of 3.3 mg/day of clonidine. In four clonidine was the only treatment and in the remaining eight clonidine was superadded to a neuroleptic regimen after symptomatology was stable. Clonidine caused reduction of scores for both productive psychotic symptoms and anxiety. Negative symptoms were unaffected. These findings are discussed with respect to the small magnitude of the effects, questions as to specificity of the effects and methodologic limitations of this pilot study.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01245253

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