ISSN:
1530-0358
Keywords:
Graft-vs.-host disease
;
Colitis
;
Colonoscopy
;
Chronic myelogenous leukemia
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Endoscopic appearance of the gastrointestinal tract of a patient with severe hemorrhagic enteric graft-vs.-host disease (GVHD) is presented. A 29-year-old man with chronic myelogenous leukemia suffered from severe enteric GVHD after allogeneic bone marrow transplantation. Endoscopy showed hemorrhagic ulceration of the upper jejunum, terminal ileum, and colon at the onset of melena. Sections of biopsies were compatible with acute GVHD. Repeat endoscopy showed gradual healing of the lesions after steroid pulse and antilymphocyte globulin therapy, but the patient died of cytomegalovirus pneumonitis 14 months later. Autopsy revealed submucosal fibrosis of the small intestine and colon.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02150747
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