ISSN:
1612-1112
Keywords:
Column liquid chromatography
;
Micellar liquid phases
;
Hybrid mobile phases
;
Retention behaviour
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary Two methods for the description of the retention behaviour of solutes in micellar liquid chromatography are compared. One of them divides the parameter space into triangular subspaces, fitting a different equation in each subspace. The second method makes use of a unique equation, valid in the whole parameter space. In both cases, equations of the type log k=f (μ, ϕ), and 1/k=f (μ, ϕ), (μ and ϕ are the concentration of surfactant and alcohol, respectively), were used to describe the retention. The use of the hyperbolic function, 1/k=c0+c1μ+c3μϕ, to describe the whole parameter space yielded the best prediction. When a small portion of the parameter space was modelled, a simpler hyperbolic function, lacking the μϕ term often led to good results. The logarithmic equations usually gave the poorer predictions.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02290358
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