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  • 1
    ISSN: 1436-2813
    Keywords: injection sclerotherapy ; esophageal varices ; doublelumened over-tube
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This report describes our data regarding repeated injection sclerotherapy using a newly designed over-tube. We treated 17 consecutive patients with esophageal varices, (3 acute, 6 elective and 8 prophylactic). An intravariceal injection of 5 per cent ethanolamine oleate was administered, using a newly designed transparent over-tube containing a second lumen for a flexible injection needle. This over-tube provides an easier, safer, shorter-in-time method of sclerosing esophageal varices. One of the 17 patients died as a result of liver failure associated with advanced cirrhosis and a concomitant hepatoma. Eradication of esophageal varices was attained in the remaining 16 patients, after an average of 5.0 injections over an average period of 5.8 weeks (range: 3–7 injections during 3–11 weeks). No complications, such as esophageal perforation or aspiration pneumonia were encountered. Recurrent variceal bleeding has not occurred during the 9 months follow-up.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1436-2813
    Keywords: extrahepatic portal venous obstruction ; esophageal varices ; shunts ; direct interruption
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Thirty patients with esophageal varices, portal venous obstruction and a histologically proven normal liver underwent either one of 2 different types of surgery. Shunt surgery was performed on 20 patients: 9 had a mesocaval shunt, 3, a splenorenal shunt, 4, a left gastric venacaval shunt, and 4, a distal splenorenal shunt. Conversely, direct interruption was performed on the other 10 patients: 6 underwent an esophageal transection, and 4 underwent a resection of the proximal stomach. Re-hemorrhage occurred in 7 of the former 20 patients but not in any of the 10 on whom the direct interruption method was used. In 6 of these 7 patients who experienced rebleeding, subsequent direct interruption surgery led to control of the bleeding. One patient died of a variceal hemorrhage one month postoperatively. The total 10 year cumulative survival rate was 86.3 per cent. In the light of these findings, we believe that methods of direct interruption, such as esophageal transection, may well be the approach of choice for patients with esophageal varices caused by extrahepatic portal venous obstruction.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 76 (1982), S. 36-39 
    ISSN: 1432-2072
    Keywords: Continuous choice ; Ethanol preference ; Position habit ; Rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Preference for ethanol in rats, overcoming the problem of a position habit, was assessed in a one-lever and two-liquid chamber. Performance in lever pressing for ethanol of different concentrations (2.5%, 5.0%, and 15.0%) and for water, as well as the amount of liquid intake, were recorded. Evidence of ethanol preference was observed by both the lever press and consumption measures when the concentration was 2.5%. Water preference was evident at higher concentrations. The present method proved to be a useful method for studying ethanol preference in rats.
    Type of Medium: Electronic Resource
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