ISSN:
1432-1106
Keywords:
Hamster
;
Corpus Callosum
;
Plasticity
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Visual callosal, corticogeniculate and corticotectal projections were examined using autoradiography and the horseradish peroxidase (HRP) technique in normal hamsters and in animals subjected to removal of both eyes at birth. The visual callosal pathway in the bilateral enucleates was markedly abnormal. The central portion of area 17 which was, for the most part, devoid of callosal cells and terminals in the normals, contained heavy callosal labelling and a large number of callosal neurons in the enucleated animals. The laminar distribution of callosal terminals in the medial part of area 17 in the enucleates was very similar to that seen near the 17-18a border in the normal animals. Label was densest in layers V and VI, light in lamina IV, and fairly dense in the supragranular layers. The laminar distribution of callosal neurons in the bilateral enucleates was, however, quite abnormal. Callosal cells were scattered, in approximately equal proportions, throughout layers II–III and V. In the normals, over 70% of all callosal neurons were in layers II–IV. The laminar origins and topography of the corticotectal and corticogeniculate projections were essentially normal in the blinded hamsters.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00237882
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