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  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Experimental brain research 3 (1967), S. 135-149 
    ISSN: 1432-1106
    Schlagwort(e): DSCT ; Corticospinal ; Inhibition ; Excitation
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Effects from the cerebral cortex on neurones of the dorsal spinocerebellar tract (DSCT) were examined: I. In group I units (units receiving monosynaptic excitation from group I fibres) repetitive stimulation of the contralateral sensorimotor cortex usually inhibited impulse transmission from the primary afferents. The inhibition had a latency of 10–20 msec and lasted for 82-100 msec or more. Discharges induced by muscle stretch were also inhibited by the cortical stimulation. DSCT units belonging to extensors and flexors were both inhibited from the cortex. In a small percentage of group I units the inhibition was preceded by a shorter-lasting excitation. 2. FRA units (units receiving excitation from cutaneous and/or high threshold muscle afferents) were typically excited by the cortical stimulation. The excitation was often followed by a period of depression of transmission from the periphery. 3. It is suggested from the effective cortical area and experiments with lesions in the medullary pyramid and in the spinal cord that the inhibition in group I units and the excitation of FRA units are both mediated by the corticospinal tract. Experiments were also made to determine the level where the cell body of a given DSCT unit is located, and the results from 56 units are presented.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Experimental brain research 3 (1967), S. 163-177 
    ISSN: 1432-1106
    Schlagwort(e): DSCT ; Postsynaptic inhibition ; Presynaptic inhibition ; Corticospinal ; Primary afferents
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Synaptic actions evoked from primary afferents and the sensorimotor cortex in neurones of the dorsal spinocerebellar tract were investigated: 1. Stimulation of the anterior lobe of the cerebellum produced a small IPSP in only one but not in the other six neurones examined. 2. IPSPs were induced not only from group I fibres (in 41% of group I neurones) but also from cutaneous and/or high threshold muscle afferents (in 37%). 3. Stimulation of the contralateral sensorimotor cortex evoked IPSPs in 80% of group I neurones. The IPSP had a latency of 10–15 msec and lasted for 40–100 msec. EPSPs were evoked from the cortex in a small number of neurones. 4. Effects from the cortex were compared with those from primary afferents in individual neurones. The cortical IPSPs were induced independently of whether the neurone received monosynaptic EPSP from extensor or flexor group I fibres. The cortical IPSPs (or EPSPs) occurred more frequently in neurones which exhibited polysynaptic IPSPs (or EPSPs) from primary afferents. 5. The few FRA neurones encountered were all excited from the cortex. Excitability measurements of primary afferent terminals in or near Clarke's column showed that a terminal depolarization is evoked from the cortex in group Ib but not in Ia afferents. The relative importance of post-and presynaptic inhibition of transmission to the DSCT is discussed.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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