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  • Memory  (2)
  • Cortisol  (1)
  • Dimethyltryptamine  (1)
  • 1
    ISSN: 1432-2072
    Keywords: Nicotine ; Cigarette smoking ; Cortisol ; Growth homone ; Prolactin ; Heart rate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Results of this study indicate that nicotine from cigarette smoking increases circulating levels of cortisol, growth hormone, and prolactin in male chronic smokers. Previous studies have not addressed the question of whether the stimulus for smoking-related hormone release is the ‘stress’ of smoking or a pharmacologic action of nicotine and other tobacco substrates. Nicotine exposure is controlled in this study by allowing each subject to smoke only two 2.0 mg nicotine cigarettes during one experimental session and two 0.2 mg nicotine cigarettes in another session. Plasma levels of cortisol, growth hormone, and prolactin for the higher nicotine session were found to be significantly elevated over those for the low-nicotine session, indicating that nicotine itself plays a predominate role in smoking-induced hormone increases. All hormone levels for the 2.0 mg nicotine session had not returned to baseline 60 min after smoking.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2072
    Keywords: Memory ; Protein Synthesis ; Cycloheximide ; Passive Avoidance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Cycloheximide, injected subcutaneously after training in a passive avoidance task resulted in impaired performances on the retest given 7 days later. A gradient was observed for this effect, injections given immediately after training producing most impairment and injections given 2 h after training producing none.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-2072
    Keywords: Chlorpromazine ; Pentobarbital ; Delayed Matching ; Motor Impairment ; Sedation ; Memory
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Monkeys trained to perform in a delayed matching test under five delay conditions were given chlorpromazine hydrochloride (0.05, 0.1, 0.2 and 0.4 mg/kg) and pentobarbital sodium (1.0, 10.0 and 20.0 mg/kg) before test sessions. Both drugs decreased response rate proportionally as dose increased. Chlorpromazine initially depressed accuracy, but showed no specific effects as delay interval increased. Pentobarbital had little effect upon accuracy, although impairment on the simultaneous conditions was seen at the highest dose. It is concluded that neither drug produced specific effects upon short-term memory.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 40 (1974), S. 211-223 
    ISSN: 1432-2072
    Keywords: Hallucinogens ; Hallucinations ; LSD ; Dimethyltryptamine ; Chlorpromazine ; Amphetamine ; Monkey Behavior
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract An attempt was made to develop an objective behavioral profile that could be used to distinguish the behavioral effects of hallucinogens from those of other classes of drugs. Saline, bromo-lysergic acid diethylamide, and two doses each of lysergic acid diethylamide (LSD), diemethyltryptamine (DMT), chlorpromazine, and d-amphetamine sulphate were administered to solitary adolescent rhesus monkeys whose behavior was observed, videotaped, and scored in a number of categories. Hallucinogens (LSD and DMT) could be distinguished from other drugs by the increased frequency of unusual behaviors such as spasms, stereotypy, and inappropriate behavior, and the decreased amount of exploration time. Hallucinogens also produced distinctive qualitative changes in behavior.
    Type of Medium: Electronic Resource
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