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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 83 (1990), S. 131-136 
    ISSN: 1432-1106
    Keywords: Vasopressin release ; Brain renin-angiotensin system ; Brain prostanoids ; Prostaglandin D2 ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Experiments were carried out in conscious, unrestrained, male rats to evaluate possible interactions between brain prostanoids and the brain renin-angiotensin system in the control of vasopressin release and in cardiovascular regulation. The intracerebroventricular (icv) administration of prostaglandin D2 (PGD2) resulted in transient increases in the plasma vasopressin concentration (PAVP) and heart rate and a gradual increase in mean arterial blood pressure (MABP). Pretreatment icv with saralasin, an angiotensin II-receptor antagonist, moderately attenuated the vasopressin response to PGD2, but had no effect on the heart rate and blood pressure responses. Angiotensin II icv increased both PAVP and MABP. This vasopressin response was almost completely prevented by prior icv meclofenamate, a cyclooxygenase inhibitor, and the blood pressure response was attenuated. These observations, combined with previous studies of the role of central angiotensin II and central prostanoids in the physiological control of vasopressin release, suggest that there may be important interactions between brain prostanoids and the brain renin-angiotensin system in this control.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1106
    Keywords: Vasopressin release ; Brain muscarinic receptors ; Brain nicotinic receptors ; Increased plasma osmolality ; Hemorrhage
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary There is considerable evidence to suggest that there is a cholinergic link in the neural control of vasopressin release, but the precise role for this link has not been adequately demonstrated in the intact animal. We have, therefore, examined in conscious unrestrained rats the effects of central cholinergic blockade on the stimulation of vasopressin release by increased plasma osmotality (iv infusion of 2.5 M NaCl at 0.1 mg/kg body weight · min for 30 min) and by decreased blood volume (2 successive hemorrhages of 10% of blood volume each). The vasopressin responses to these stimuli were unaffected by either intracerebroventricular (icv) atropine (10 μg; muscarinic blockade) or icv hexamethonium (10 μg; nicotinic blockade) in doses which block the vasopressin responses to icv cholinergic agonists. The implications of these findings are discussed.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Astrophysics and space science 231 (1995), S. 127-130 
    ISSN: 1572-946X
    Keywords: Gamma-ray bursts ; Counterparts ; Instrumentation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The BATSE and OSSE instrument teams have modified flight software to promptly (within 2 min of trigger) slew the OSSE detectors to burst locations determined on-board by BATSE. This enables OSSE to make sensitive searches for prompt and delayed post-burst line and continuum emission above 50 keV. In the best cases our sensitivity will be more than an order of magnitude better than any other search in this energy range. We expect to slew to 1–2 bursts per month, based on the OSSE FOV and BATSE event rate. Detections or limits from continued operation of this system may provide significant constraints on burst models. As an example of the observations made using this system, we present preliminary limits for post-burst emission from GRB 950223 on several time scales.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Astrophysics and space science 231 (1995), S. 123-126 
    ISSN: 1572-946X
    Keywords: Gamma-ray bursts ; Counterparts
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The existence of either pre- or post-burst emission can provide substantial new information about the burst source and its local environment. We have data from serveral events serendipitously in or near the OSSE field of view at the time of the burst. We present pre- and post-burst flux limits from one such event, GRB 940301. The OSSE data for other periods when scheduled observations have included burst locations will enable us to search for pre- and post- burst emission on many time scales.
    Type of Medium: Electronic Resource
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