ISSN:
1612-1112
Keywords:
Reversed-phase TLC
;
Crown ether derivatives
;
Quantitative-Structure-Activity Relationship
;
Lipophilicity
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary The lipophilicity of 28 modified crown ether derivatives was determined by reversed-phase thin-layer chromatography (RPTLC) using various organic phases and supports. The lipophilicity values determined in different RPTLC systems showed good correlations, however the quality of the organic phase (methanol, acetone, acetonitrile) and the support characteristics influenced to a small extent the determination.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02259698
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