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  • 1
    Electronic Resource
    Electronic Resource
    The value of testicular biopsy in cryptorchidism (1984)
    Springer
    Urological research 12 (1984), S. 171-174 
    Details
    ISSN: 1434-0879
    Keywords: Testicular biopsy ; Cryptorchidism ; Fertility ; FSH ; LH ; T ; Estradiol
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary This prospective study conducted on 24 children, who have now reached adulthood, was undertaken to determine the value of testicular biopsies in cryptorchidism relative to fertility prognosis. A significant correlation between the number of germ cells in the biopsy and sperm count was found to exist (p〈5%). Thus, the testicular biopsy performed during orchiopexy was found to have a prognostic value. The hormonal findings (LH, FSH) suggest that in cryptorchid adults impaired Leyding cell function exists prognostic value with respect to fertility and the probability of discovering carcinoma in situ cells, it is strongly recommended that a testicular biopsy is performed in cryptorchid boys.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00255917
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Screening for cryptorchid boys risking sterility and results of long-term buserelin treatment after successful orchiopexy (1987)
    Springer
    European journal of pediatrics 146 (1987), S. S59 
    Details
    ISSN: 1432-1076
    Keywords: Cryptorchidism ; Biopsy ; Risk group ; Fertility ; Buserelin treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This long-term prospective follow-up study showed that in cryptorchid patients a significant correlation exists between the number of germ cells at the time of orchiopexy (prepuberty) and the spermiogram, and thus a biopsy has a prognostic value. Fifty percent of our patients had a germ cell count of 〈0.1 per tubule and belong to the risk group for sterility. Successful surgery could not induce a significant increase of germ cells in the risk group, although it does prevent secondary testicular damage. Patients with cryptorchidism developed after birth have significantly better chances of fertility than those with primary cryptorchidism. The priming effect of testosterone in the first months of life is important for male fertility. In patients belonging to the risk group treated with buserelin, a significant age-dependent increase in germ cell count occurred.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00452877
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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