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  • 1
    ISSN: 1530-0358
    Keywords: Colon cancer ; Curative resection ; follow-up
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The follow-up of patients after potentially curative resection of colon cancer has important clinical and financial implications for patients and society, yet the ideal surveillance strategy is unknown. PURPOSE: The aim of this study was to determine the current follow-up practice pattern of a large, diverse group of experts. METHODS: The 1,663 members of The American Society of Colon and Rectal Surgeons were asked, via a detailed questionnaire, how often they request nine discrete follow-up evaluations in their patients treated for cure with TNM Stage I, II, or III colon cancer over the first five post-treatment years. These evaluations were clinic visit, complete blood count, liver function tests, serum carcinoembryonic antigen (CEA) level, chest x-ray, bone scan, computerized tomographic scan, colonoscopy, and sigmoidoscopy. RESULTS: Forty-six percent (757/1663) completed the survey and 39 percent (646/1663) provided evaluable data. The results indicate that members of The American Society of Colon and Rectal Surgeons generally conduct follow-up on their patients personally after performing colon cancer surgery (rather than sending them back to their referral source). Routine clinic visits and CEA levels are the most frequently performed items for each of the five years. The large majority (〉75 percent) of surgeons see their patients every 3 to 6 months for years 1 and 2, then every 6 to 12 months for years 3, 4, and 5. Approximately 80 percent of respondents obtain CEA levels every 3 to 6 months for years 1,2, and 3, and every 6 to 12 months for years 4 and 5. Colonoscopy is performed annually by 46 to 70 percent of respondents, depending on year. A chest x-ray is obtained yearly by 46 to 56 percent, depending on year. The majority of the members of The American Society of Colon and Rectal Surgeons do not routinely request computerized tomographic scan or bone scan at any time. There is great variation in the pattern of use of complete blood count and liver function tests. Members of The American Society of Colon and Rectal Surgeons from the United States tend to follow their patients more closely than do those living in other countries. The intensity of follow-up does not markedly vary across TNM Stages I to III. CONCLUSION: The surveillance strategies reported here rely most heavily on clinic visits and CEA level determinations, generally reflecting guidelines previously proposed in the current literature.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Hydrobiologia 344 (1997), S. 181-193 
    ISSN: 1573-5117
    Keywords: Shock load impacts ; impacts of sporadic toxic discharges ; threshold activated pump sampler ; biological monitoring ; riverine wetlands ; macrophyte indicator assemblages ; Daphnia magna ; Notropis atherinoides ; acute toxicity ; chronic toxicity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Shock loading of toxic substances into natural waterways is apervasive practice which has substantial impacts on their biota.This paper describes the effects of shock (pulse) pollution loadingfrom two major industries on a river and wetland system in southernOntario, Canada. The assessment of shock loading frequencyindicated that sporadic discharges of polluted water occurred onaverage once every other day during the 38 days of monitoring inthe period April, 1986 to November, 1987.To estimate the frequency and intensity of the shock loads, anautomatic pump sampler that was activated by a thresholdconductivity was constructed and deployed. Samples were withdrawnfrom the river when the specific conductivity of the streamexceeded a threshold value of two times background. Backgroundspecific conductivity ranged between 200–250 μS cm-1The impact of these shock load discharges on a downstream aquaticplant community in a Class One (Provincially Significant) wetlandwas examined. The area of Thompson‘s Creek upstream of the CyanamidChemical Company displayed a normal complement of aquatic organismswhile downstream of the company‘s main discharges for a distance ofnearly 2 km, the stream was barren of nearly all aquatic life.A reef-like structure in which nickel, chromium, and lead reachedrespectively 2900, 2100 and 2210 mg kg-1 dry weight ofsediment was located in the Welland River near the outfall of theAtlas-Mansfield storm sewer adjacent to the Atlas Specialty SteelsCompany. The average flow rate at the outfall of theAtlas-Mansfield storm sewer into the Welland River wasapproximately 28 400 m3 day-1 in 1986 (MOE 1987). Asmall area referred to as the Atlas reef because of the high ironconcentrations giving the sediments a cement-like condition, wasdevoid of all higher aquatic plants.
    Type of Medium: Electronic Resource
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