ISSN:
1439-6327
Keywords:
Potassium
;
Catecholamines
;
Cyclic AMP
;
Exercise
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Serum potassium, aldosterone and insulin, and plasma adrenaline, noradrenaline and cyclic adenosine 3′:5′-monophosphate (cAMP) concentrations were measured during graded exhausting exercise and during the following 30 min recovery period in six untrained young men. During exercise there was an increase in concentration of serum potassium (4.74 mmol·1−1, SEM 0.12 at the end of exercise vs 3.80 mmol·1−1, SEM 0.05 basal,P〈0.001), plasma adrenaline (2.14 nmol·1−1, SEM 0.05 at the end of exercise vs 0.30 nmol·1−1, SEM 0.02 basal,P〈0.001), plasma noradrenaline (1.10 nmol·1−1, SEM 0.64 at the end of exercise vs 1.50 nmol·1−1, SEM 0.05 basal,P〈 0.001), serum aldosterone (0.92 nmol·1−1, SEM 0.14 at the end of exercise vs 0.36 nmol·1−1, SEM 0.05 basal,P〈0.01), and plasma cAMP (35.4 nmol·1−1, SEM 2.3 at the end of exercise vs 21.4 nmol·1−1, SEM 4.5 basal,P〈0.05). While concentrations of serum potassium, plasma adrenaline and cAMP returned to their basal levels immediately after exercise, those of plasma noradrenaline and serum aldosterone remained elevated 30 min later (1.90 nmol·1−1, SEM 0.01,P〈0.01; and 0.85 nmol·1−1, SEM 0.12,P〈0.01, respectively). Serum insulin concentration did not change during exercise (6.47 mlU·1−1, SEM 0.58 at the end of exercise vs 5.47 mlU·1−1, SEM 0.41 basal, NS) but increased significantly (P〈0.02) at the end of the recovery period (7.12 mlU·1−1, SEM 0.65). Serum potassium increases with exhausting exercise appeared to be caused not only by its release from contracting muscles but also by an α-adrenergic stimulation produced by adrenaline and noradrenaline. On the other hand, the increased levels of plasma noradrenaline maintained during the recovery period may have served to avoid excessive hypokalaemia through the stimulation of muscle α-receptors. Thus, catecholamines may play an important role in the regulation of serum potassium concentrations during and after exercise. Any disturbance of these adrenergic effects may lead either to an excessive increase or to a decrease of kalaemia, with the consequent risk of arrhythmias linked to exercise.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00571555
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