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  • 1
    Electronic Resource
    Electronic Resource
    The value of second-look operation in patients with advanced epithelial ovarian carcinoma (1989)
    Springer
    Archives of gynecology and obstetrics 244 (1989), S. 79-86 
    Details
    ISSN: 1432-0711
    Keywords: Advanced ovarian carcinoma ; Diagnostic second-look ; Cytoreductive second-look
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A second-look operation was performed on 151 patients with stage III and IV epithelial ovarian carcinoma who had responded to primary surgery and chemotherapy. 19% of the 79 patients who appeared clinically to be free of disease had microscopic recurrences and 23% had macroscopic residual disease at a second-look operation. The 5-year survival rate for patients with no histological and for those with microscopic secondaries at second-look operation were 55% and 35% respectively (P=0.45). Only patients with well or moderately well differentiated tumors and a small residual tumor mass at first operation had a good prognosis after a second-look operation even without further chemotherapy. Median survival after secondary debulking was 15 to 17 months and was independent in the radicality of the second-look procedure. Outside of clinical trials second-look laparotomy should therefore only be performed as a diagnostic procedured as a diagnostic procedure in patients with well or moderately well differentiated tumors who are left with a small residual tumor mass at the time of the first operation. Because this is a group of patients in whom chemotherapy can be discontinued after a negative second-look operation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00931377
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Angiotensin converting enzyme activity in children with congenital heart disease (1990)
    Springer
    European journal of pediatrics 150 (1990), S. 19-21 
    Details
    ISSN: 1432-1076
    Keywords: Serum angiotensin converting enzyme activity ; Congenital heart disease ; Pulmonary blood flow ; Pulmonary arterial pressure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Serum angiotensin converting enzyme (ACE) activity was determined in 46 children with congenital heart disease with normal and abnormal lung perfusion: (1) congenital heart disease with normal pulmonary blood flow (12 patients); (2) congenital heart disease with increased pulmonary blood flow (18 patients); (3) congenital heart disease with decreased pulmonary blood flow (16 patients). There was no significant difference in serum ACE activity between the three groups. In group 2 serum ACE activity had a tendency to correlate inversely with both mean pulmonary arterial pressure (r=−0.43;P≤0.05) and pulmonary vascular resistance (r=−0.48;P=0.05). No further correlations between serum ACE activity and age, serum electrolytes, creatinine nor other haemodynamic data could be established.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01959472
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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