ISSN:
1617-4623
Keywords:
Cytotype
;
Drosophila
;
Gene expression
;
P-element
;
Vestigial
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary A series of P-element insertion mutations at one site in the vestigial (vg) locus was tested for cytotype dependent effects on vg expression. The mutant phenotypes for four P-element vg alleles were suppressed when the alleles were stabilized in the P-cytotype. The suppression was observed whenever repressor-producing P-elements were present in the genome. Genetic and molecular analysis indicated that the suppression is not due to excision or other irreversible alterations of the inserts. The results are consistent with a model in which somatic P-element repressor binding to the ends of P-element inserts can modify the effects of these inserts on target gene expression.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00334709
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