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  • 1
    Electronic Resource
    Electronic Resource
    Plasma N-acetyl-β,D-glucosaminidase activities and glycaemia in diabetes mellitus (1983)
    Springer
    Diabetologia 24 (1983), S. 433-436 
    Details
    ISSN: 1432-0428
    Keywords: N-acetyl-β ; D-glucosaminidase ; hyperglycaemia ; glycosylated haemoglobin ; insulin infusion ; diurnal variation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The plasma activity of the lysosomal enzyme N-acetyl-β, D-glucosaminidase (NAGase) has been shown to correlate with hyperglycaemia; their temporal relationships have been investigated. In 12 insulin-treated male diabetic patients, NAGase showed a slight diurnal variation with a nadir at 07.00 h (F=9.54, p〈0.001). The mean plasma glucose and NAGase fluctuated similarly (rs=0.88, p〈0.01) but did not correlate within individual patients. Normoglycaemia was induced in eight insulin-treated diabetic patients for 4 days but the mean NAGase did not fall significantly. Glycaemic improvement over 3 months was achieved by dietary therapy in 28 newly-presenting non-insulin-dependent diabetic patients: there were significant falls in mean fasting plasma glucose (mean±SD: 12.8±3.3 to 8.3±3.1 mmol/l; p〈0.001), glycosylated haemoglobin levels (12.4±2.4 to 9.3±2.3%, p〈 0.001) and a corresponding decrease of NAGase (1.5±0.5 to 1.2±0.4 μmol 4-nitrophenyl-N-acetyl-β-D-glucosamide released.h−1.ml−1; p〈0.001). The change in NAGase correlated with the changes in plasma glucose and glycosylated haemoglobin levels (r = 0.61, p〈0.025; r = 0.48, p〈0.05, respectively). Plasma NAGase activity may be influenced by glycaemia in diabetes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00257342
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Contact sex pheromone in the tsetse flyGlossina pallidipes (Austen) Identification and Synthesis (1984)
    Springer
    Journal of chemical ecology 10 (1984), S. 429-450 
    Details
    ISSN: 1573-1561
    Keywords: Glossina ; pallidipes ; tsetse fly ; Diptera ; Muscidae ; pheromone ; contact stimulant ; branched alkane ; 13,23-dimethylpentatriacontane
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Adult maleG. pallidipes attempted to copulate with decoys treated with a branched paraffin obtained from laboratory-reared female flies. The compound causing maximal response was isolated and identified as 13,23-dimethylpentatriacontane. The synthesized compound elicited increasing responses with increasing doses. This sex- and species-specific compound was always present in physiological amounts in females, as it increased from 2 μg at emergence to 10 μg per female at 14 days. It was present in wild-caught females from a wide geographical range.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00988090
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Compared behavioral responses of maleDrosophila melanogaster (Canton S) to natural and synthetic aphrodisiacs (1985)
    Springer
    Journal of chemical ecology 11 (1985), S. 1617-1629 
    Details
    ISSN: 1573-1561
    Keywords: Drosophila melanogaster ; Diptera ; Drosophilidae ; aphrodisiac pheromone ; recognition pattern ; cuticular hydrocarbons ; heptacosadienes ; mass spectrometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Cuticular aphrodisiacs fromD. melanogaster females were further characterized and the male response specificity towards such natural and synthetic unsaturated hydrocarbons was investigated. The behavioral activity seems to be correlated with some chain-length requirement and double-bond position; at least one double bond in position 7 seems necessary. This position is more abundant among natural monoenes, and among dienes which also bear a second double bond in position 11, whatever the chain length. Bioassays of the synthetic (Z,Z)-7,11-heptacosadiene yielded a dose-response curve close to that of the natural mixture of heptacosadienes in which the 7–11 isomer is predominant. This female specific 7,11 heptacosadiene appears to be the most potent aphrodisiac for males of the species. Its threshold is lower than that of both 7,11-nonacosadiene and 7-pentacosene which might also play a role in sex and species recognition.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01012116
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    Paper (German National Licenses)
    Fulltext
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