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  • 1
    Electronic Resource
    Electronic Resource
    Methanogenium, a new genus of marine methanogenic bacteria, and characterization ofMethanogenium cariaci sp. nov. andMethanogenium marisnigri sp. nov. (1979)
    Springer
    Archives of microbiology 121 (1979), S. 147-153 
    Details
    ISSN: 1432-072X
    Keywords: Methanogenium cariaci ; Methanogenium marisnigri ; Marine methanogenic bacteria ; Ultrastructure ; TaxonomyMethanogenium gen. nov.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A new genus of marine methanogenic bacteria and two species within this genus are described.Methanogenium is the proposed genus andMethanogenium cariaci the type species. Cells of the type species are Gram-negative, peritrichously flagellated, irregular cocci with a periodic wall surface pattern. Colonies formed by these bacteria are yellow, circular and umbonate with entire edges. The DNA base composition is 52 mol% guanine plus cytosine. Formate or hydrogen and carbon dioxide serve as substrates for growth. Cells ofMethanogenium marisnigri are of similar shape but smaller diameter thanM. cariaci. The colonies ofM. marisnigri are convex, and the DNA base composition is 61 mol % G+C. Formate or hydrogen and carbon dioxide are growth substrates. Sodium chloride is required for growth of both methanogens.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00689979
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  • 2
    Electronic Resource
    Electronic Resource
    Chromosome analysis of two rat tumor cell lines possible role of DMs and HSR in metastasis (1984)
    Springer
    Journal of cancer research and clinical oncology 107 (1984), S. 172-177 
    Details
    ISSN: 1432-1335
    Keywords: Two rat tumor cell lines ; Karyotype/G-banding ; DMs/HSR ; Metastasis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The rat tumor cell lines BSp73AS (AS, nonmetastasizing with pronounced adherent capacities) and BSp73ASML (ASML, highly metastasizing with reduced adherent capacities) were cytogenetically investigated. The ASML cell line.is reportedly derived from the AS cell line. Both lines exhibited abnormal numerical and structural chromosomal characteristics. The metastasizing ASML cells showed a higher chromosome number (modal number: 62–63) than the nonmetastasizing AS cells (modal number: 48). The AS karyotype was characterized by the presence of a large metacentric marker chromosome resulting from a Robertsonian translocation (Rb 6.7). This chromosome is as such absent in ASML cells but perhaps it may be present in these cells with a major part of chromosome 7 being deleted. The most interesting feature of the ASML karyo-type was the presence of double minutes (DMs) and a homogeneously staining region (HSR) at the telomeric end of chromosome 6. These were peculiar to the ASML cells, being absent in the AS cells. DMs and HSR are reported to be correlated with the resistance to various drugs and with the acquired virulence of tumor cells through gene amplification. Therefore, we assume that in the metastasizing ASML cell line the DMs and HSR were established through genetic selection and that they are probably related to the acquired metastasizing capacity of these cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01032603
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    Paper (German National Licenses)
    Fulltext
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