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  • 1
    ISSN: 1435-1536
    Keywords: Key words Monolayers ; bidimensional compatibility ; miscibility ; MacroDerm A ; MacroDerm L ; penetration enhancers
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract  Spread monolayers of two new skin permeation enhancers, MacroDerm A and MacroDerm L were investigated at the water/air interface as a function of temperature and of subphase composition. Both components did not seem to be markedly affected by changes in ionic strength and by the presence of metal ions in the subphase. The two-dimensional binary system MacroDerm A –MacroDerm L was also studied at the water/air interface at 298 K on pure water subphase. The behavior of surface areas, surface compressional moduli and collapse pressure as a function of molar ratios of components shows that MacroDerm A and MacroDerm L are miscible.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of thermal analysis and calorimetry 61 (2000), S. 551-564 
    ISSN: 1572-8943
    Keywords: amphiphile oligomers ; DSC ; thermo-reversible gelation ; water states
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Symmetrical block oligomers having in common terminal groups (A) consisting of polyoxyethylene (20) stearyl ether are materials of pharmaceutical and cosmetic interest. Phase properties of their aqueous systems and amounts of water typologies were determined by differential scanning calorimetry (DSC). The overall amount of water absorbed by each investigated oligomer was not significantly influenced by the type of central bridging block, whereas the amount of free water decreased with increasing oligomer concentration in the gel. A number of 60–70 moles of water was found to solvate the oligomer chain. The oligomers studied presented a thermo-reversible gelation with and precipitation under determined temperature conditions.
    Type of Medium: Electronic Resource
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