Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    ISSN: 1432-2072
    Keywords: Morphine ; Naloxone ; Dependence ; Aggression
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Weight loss and shock-elicited aggression have been compared as quantitative indices of morphine abstinence in rats. A range of doses of morphine was administered to rats by i.p. injection twice daily for 12–15 days. After injections were stopped, morphine-abstinent rats lost weight precipitously, and showed an increased frequency of fighting in response to aversive stimulation (foot-shock). Recovery of weight appeared complete after 15–20 days but a significant increase in aggression was found at 18 days post-withdrawal; this virtually disappeared after 52 days. Both the amount of weight lost and the frequency of fighting increased as a function of the previous maintenance dose of morphine; the effective dose range appeared similar for these two indices. Weight loss was much less variable than fighting, had the advantage of rapid, objective measurement, and appeared to be the more reliable index of abstinence.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Documenta ophthalmologica 50 (1981), S. 371-388 
    ISSN: 1573-2622
    Keywords: Static perimetry ; Acuity profile perimetry ; Photopic ; Mesopic ; Scotopic adaptation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Effects of target size, eccentricity and background luminance were determined for static and acuity profile perimetry in the central 30° radius of the visual field. Reductions in target size produced decreases in sensitivity for both functions, with acuity profiles (resolution sensitivity) being more affected than static profiles (detection sensitivity). At photopic background luminances, detection sensitivity was greatest at the fovea and progressively declined with increasing eccentricity; lower background luminances produced greater detection sensitivity for the near periphery than for the fovea. Resolution sensitivity for small targets (20/80 or less) exhibited a rapid decline with increasing eccentricity that was relatively independent of background luminance, whereas large targets (20/125 or greater) revealed findings similar to the detection sensitivity results. The relative contributions of rods and cones to threshold visual responses thus appear to depend on the type of visual task, target size, eccentricity, background luminance and thek interactions. These data provide a comparison basis for future evaluations of patients with photoreceptor dysfunction.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...