ISSN:
1432-0533
Keywords:
Key words β-Amyloid precursor protein
;
Head injury
;
Diffuse axonal injury
;
Immunocytochemistry
;
Diagnosis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract β-Amyloid precursor protein immunostaining has recently been shown to be a reliable method for detecting the damage to axons associated with fatal head injury. In an attempt to compare the efficacy of this technique with conventional histological detection of axonal damage, we have reanalysed sections from a large well-characterised series of head-injured and control patients. The results indicate that the frequency of axonal injury has been vastly underestimated using conventional silver techniques, and that axonal injury may in fact be an almost universal consequence of fatal head injury.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00571509
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