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  • 1
    Electronic Resource
    Electronic Resource
    Treatment of lumbo-ischialgias of different origins by intradiscal injection of chymopapain (discolysis) (1982)
    Springer
    Acta neurochirurgica 61 (1982), S. 73-88 
    Details
    ISSN: 0942-0940
    Keywords: Discolysis ; disc prolapse ; disc protrusion ; disc operation ; lumbar ; stenosis ; spondylolisthesis ; spondylodiscitis ; lumboischialgia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An analysis is given of a series of 25 patients suffering from lumboischialgic pain of different causes, which have been treated by discolysis. Literature reports are taken into consideration. As a result of analysis, the following statements seem justified: In no kind of lumbar disc prolapse are the results of discolysis superior to those of modern operative treatment. Discolysis results are indisputably worse in cases with the usual operative indication, which consists of neurological deficit and large disc prolapse. Favourable results by discolysis can be obtained in cases with disc protrusion or small prolapse, but these cases can mostly be cured also by consequent conservative treatment. Contraindications are marked neurological deficit, demonstration of a large disc prolapse by contrast methods, Verbiest's stenosis of the lumbar spinal canal, low back pain and ischialgia without positive proof of a disc protrusion, cases with low back pain as the main or only feature, spondylolisthesis. Disc prolapse recurrences after discolysis often occur about one month afterwards. Structural instability at this stage is likely. Therefore, as with post-operative treatment, it is advisable to avoid major physical stress for the first weeks after discolysis. Major complications after discolysis are possible, and have occurred. Because discolysis offers no real advantages but some shortcomings compared to conservative treatment for disc protrusions, and to operative treatment in real disc prolapses, its justification seems more than questionable.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01740073
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    25. Pathophysiologie der Mehrfachverletzungen —Störungen des Zentralnervensystems (1974)
    Springer
    Langenbeck's archives of surgery 337 (1974), S. 191-194 
    Details
    ISSN: 1435-2451
    Keywords: Brain Injuries ; Brain Edema ; Autoregulation of the Cerebral Circulation ; Raised Intracranial Pressure ; Cerebrale Durchblutungsautoregulation ; Intrakranielle Drucksteigerung ; Traumatische Hirnschädigung ; Hirnödem
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Der Hirnverletzte ist wegen der Gefahr traumatischer intrakranieller Hämatome und wegen des Ausfalles der schützenden Durchblutungsautoregulation des Gehirns besonders gefährdet. Blutdruckabfall, Anämie, verminderterpO2 des Blutes und Temperaturanstieg, die vom Hirngesunden ohne Schaden toleriert werden, können die Verletzungsfolgen entscheidend verschlimmern. Die therapeutischen Konsequenzen werden besprochen.
    Notes: Summary The patient with head injuries is particularly at risk, due to the possibility of intracranial hematomas and the failure of the autoregulation of the cerebral circulation. A fall in blood pressure and oxygenation, anemia, and/or increased body temperature, which are tolerated with no harm by patients who have not suffered brain damage, can make the results of injury significantly worse. The therapeutic consequences are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01278657
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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