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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 60 (1983), S. 145-148 
    ISSN: 1432-0533
    Keywords: Intracytoplasmic acidophilic granules ; Distribution ; Lewy bodies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Using four autopsied brains, we studied the anatomic locations of the intracytoplasmic acidophilic granule (IAG)-containing neurons. These neurons occurred in the hypothalamus, zona incerta, insular cortex, and the other 23 nuclei. However, IAGs were not observed in neurons of the Ammon's horn, thalamus, dentale nucleus, or in Purkinje cells of the cerebellum. The distribution of IAG-containing neurons does not exactly correspond to that of the neuromelanin- or monoamine-forming neurons. There is, however, a striking parallelism between the IAG-containing neurons map and the Lewy bodies map. It is suggested by the superimposition of both maps that IAG-containing neurons may have a certain metabolic relation to the formation of Lewy bodies.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0533
    Keywords: Juvenile parkinsonism ; Substantia nigra ; Central pale area ; Early Lewy body
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Neurons containing a central pale area which may possibly represent an early cytoplasmic change before Lewy body maturation were observed in the substantia nigra from a rare autopsy case of juvenile parkinsonism. Ultrastructurally, such neurons exhibited cytoplasmic swelling along with disappearance of the rough endoplasmic reticulum from the central part of the perikaryon. The pale central cytoplasm was replaced by numerous-cored vesicles, mitochondria, ribosomelike granules and a few Lewy body filaments. The relation of this central pale area to the pale body is discussed.
    Type of Medium: Electronic Resource
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