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  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Digestive diseases and sciences 36 (1991), S. 917-923 
    ISSN: 1573-2568
    Schlagwort(e): gastric emptying ; mouth-to-cecum transit ; whole-gut transit ; chronic alcoholism
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Gastric emptying, mouth-to-cecum transit, and whole-gut transit of a solid-liquid meal were measured in 46 chronic alcoholics and in 30 control subjects by using scintigraphic techniques, hydrogen breath test, and stool markers. In the alcoholics various parameters such as ethanol consumption, gastrointestinal symptoms, and alcoholic neuropathy were determined and related to gastrointestinal transit times. Although there was no significant overall difference of gastric emptying, abnormally delayed gastric emptying was detected in 23.9% of the alcoholics but no control subject (P〈0.005). Mouth-to-cecum transit was significantly prolonged in the alcoholics (P〈0.001) with 14 alcoholics (37.8%) disclosing delayed mouth-to-cecum transit. No significant differences between both groups were detected concerning whole gut transit. In the alcoholics there was a significant correlation of dyspeptic symptoms with delayed gastric emptying (P〈0.006), and alcoholics with diarrhea had an accelerated mouth-to-cecum transit as compared to those without diarrhea (P〈0.05). Neither the presence of autonomic or peripheral neuropathy nor the presence of liver cirrhosis or ascites was significantly related to gastrointestinal transit times. However, the daily ethanol ingestion significantly correlated with gastric emptying (P〈0.005). It is concluded, therefore, that in chronic alcoholics the small intestine and the stomach are most likely to be affected by gastrointestinal transit disorders and that these transit abnormalities are potentially related to toxic damage of gastrointestinal smooth muscle.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    ISSN: 1573-2568
    Schlagwort(e): progressive systemic sclerosis ; esophageal transit ; gastric emptying ; intestinal transit ; gastrointestinal symptoms ; small intestinal bacterial overgrowth
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Liquid esophageal transit and gastric emptying, mouth-to-cecum transit, and whole gut transit of a solid-liquid meal were measured in 14 patients with PSS, 16 control subjects (esophageal transit), and 20 control subjects (gastrointestinal transit), respectively, by using scintigraphic techniques, the hydrogen breath test, and stool markers. In patients with PSS, the glucose hydrogen breath test for detection of small intestinal overgrowth was performed and various gastrointestinal symptoms were determined. Esophageal transit and gastric emptying were significantly prolonged in PSS patients with 11 of 14 PSS patients (79%) disclosing delayed esophageal transit and eight of 14 PSS patients (57%) disclosing delayed gastric emptying. All PSS patients with prolonged gastric emptying also had delayed esophageal transit and there was a significant positive correlation between esophageal transit and gastric emptying (r=0.696,P〈0.01). No significant differences between PSS patients and controls were detected concerning mouth-to-cecum transit and whole gut transit, but abnormally delayed mouth-to-cecum transit was found in four of 10 PSS patients (40%) and abnormally prolonged whole gut transit was detected in three of 13 PSS patients (23%). Small bacterial overgrowth was diagnosed in three of 14 PSS patients (21%). Delayed esophageal transit and gastric emptying were associated with dysphagia, retrosternal pain, and epigastric fullness, while prolonged whole gut transit was associated with constipation. It is concluded that delayed gastric emptying is frequently associated with esophageal transit disorders in PSS patients and may be one important factor for the development of gastroesophageal reflux disease in these patients.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Digestive diseases and sciences 39 (1994), S. 565-570 
    ISSN: 1573-2568
    Schlagwort(e): gastric emptying ; antral motility ; gallbladder emptying ; progressive systemic sclerosis ; ultrasound
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Gastric emptying, antral motility, and gallbladder emptying after a liquid fatty meal were studied by ultrasound in 25 patients with progressive systemic sclerosis and in 25 sex- and age-matched controls. In patients with systemic sclerosis, the possible role of autonomic dysfunction was evaluated by four noninvasive cardiovascular reflex tests. Despite a significant delay of gastric emptying and a significant postprandial antral hypomotility in the patients with systemic sclerosis, the fat-induced gallbladder emptying was only slightly reduced, reaching no significant level when compared to the controls. The prolongation of gastric emptying correlated significantly with the duration of the disease. Although 36% of the patients in the systemic sclerosis group exhibited signs of autonomic cardiac dysfunction, there was no evidence of an association between these signs and gastric motor dysfunction. In conclusion motility disorders of the gallbladder seem to play a minor role in the upper gut involvement of systemic sclerosis, whereas motility disorders of the stomach are frequent and can be easily recognized noninvasively by real-time ultrasound.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    Springer
    Langenbeck's archives of surgery 372 (1987), S. 845-846 
    ISSN: 1435-2451
    Schlagwort(e): Intrathoracic stomach ; 24 h pH measurement ; Gastric drainage ; Intrathorakaler Magen ; 24 h pH-Metrie ; Drainageoperation des Magens
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung 11 Patienten mit einer distalen Resektion des Oesophagus und einer Oesophagogastrostomie in Höhe der Trachealbifurkation (n = 5) und einer transabdominalen subtotalen Oesophagektomie ohne Thoracotomie (n = 6) wurden untersucht. Es wurden keine Drainageoperationen ausgeführt. 6 Patienten hatten ein Plattenepithel-, 3 ein Adenocarcinom des Oesophagus, 2 ein Kardiacarcinom. Die Patienten wurden endoskopisch bis zu 8mal untersucht, jeder Patient hatte mindestens ein postop. CT, 4 Patienten wurden 24 h pH-metriert. 7 Patienten hatten eine Oesophagitis, 5 eine Gastritis. Obwohl die Mehrzahl der Patienten Speisereste im Magen zeigte, wurde bei keinem tumorfreien Patienten eine Magenausgangsstenose beobachtet. Eine primäre Drainageoperation des Magens halten wir daher für nicht indiziert.
    Notizen: Summary Eleven patients with distal resection of the esophagus and esophagogastrostomy at the level of the tracheal bifurcation (n = 5), as well as transhiatal esophagectomy without thoracotomy (n = 6), were studied. No drainage procedures were carried out. Three patients had an adenocarcinoma and 6 squamous cell carcinoma of the esophagus. Two patients presented with carcinoma of the cardia. The patients were examined endoscopically up to 8 times. In each patient at least one postoperative CAT scan was carried out; pH was measured for 24 h in 4 patients. Seven had esophagitis and 5 had gastritis of various degrees. Although the majority of the patients had food remains in the stomach, no gastric outlet stenosis was observed. Thus a primary gastric drainage operation is not necessary.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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