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The effects of pre-exposure to scopolamine on subsequent drug state discrimination (1976)

McKim, W. A.

Springer

Psychopharmacology 47 (1976), S. 153-155

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ISSN: 1432-2072

Keywords: Scopolamine ; Dissociation ; Drug state discrimination ; Generalization

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract This experiment was done to test the prediction that preexposure to a drug state would increase the discriminability of that drug state when used as a cue in a discrimination task. Eight rats were pre-exposed to scopolamine for 20 days and 8 rats were given saline injections. The drug preexposed animals acquired a drug state discrimination more quickly than the controls. A difference was also found between the generalization gradients for each group with the pre-exposed group showing a steeper generalization gradient.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00735814

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