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  • 1
    ISSN: 1432-2013
    Keywords: Hydrostatic pressure ; Edema ; Hydraulic conductivity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The influence of hydrostatic pressure elevation on fluid absorption by the isolated guinea pig gallbladder was determined following addition of various smooth muscle spasmogens to the serosal bathing medium. Acetylcholine, prostaglandin E1 and ouabain increased intraluminal presure from about 4 cm H2O to 13 cm H2O. The pressure increase was associated with a marked but transient stimulation in fluid transfer. The same phenomenon was observed following an increase in hydrostatic pressure by addition of Ringer's solution to the gallbladder lumen. Evidence is presented to support the hypothesis that this phenomenon represents the extrusion of an edema from the gallbladder wall. Two observations favour this explanation: 1. The wet weights of gallbladder subjected to high intraluminal hydrostatic pressure were only one third of those at low pressure. 2. Microscopic examination of the wall of gallbladders at low pressure showed a marked submucosal edema.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 41 (1991), S. 619-620 
    ISSN: 1432-1041
    Keywords: Lignocaine ; Prilocaine ; EMLA ; local anaesthesia ; topical administration ; clinical chemistry tests ; haematology tests
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Blood samples were taken from both antecubital veins in ten healthy volunteers. One side was anaesthetized beforehand with EMLA® cream covered with an occlusive dressing for 1 h and the other side served as a control. 19 routine clinical chemistry and haematology measurements were made. There were no clinically relevant alterations in any of the measurements. It is concluded that EMLA cream can be used to anaesthetize normal skin before blood sampling without any risk of distorting the results of the analyses of the blood.
    Type of Medium: Electronic Resource
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