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Digitale Medien

Epidermis and lymphocyte interactions during a tuberculin skin reaction (1988)

Larsen, C. G. ; Ternowitz, T. ; Larsen, F. G. ; [weitere]

Springer

Archives of dermatological research 280 (1988), S. 83-88

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Details

ISSN: 1432-069X

Schlagwort(e): Epidermis ; ETAF ; Interleukin 1 ; Mixed skin lymphocyte reaction ; Tuberculin skin test

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary Forty-one persons were tested for tuberculin skin reactivity. Epidermal cells (ECs) were isolated from the tuberculin reaction and from a contra lateral, non injected skin area. We found a significant increase of epidermal thymocyte activating factor (ETAF) in epidermis overlying a positive tuberculin reaction together with an increase of OKT6 and class II (HLA-DR) positive cells. Allogeneic lymphocytes proliferated significantly more when mixed with ECs from a positive tuberculin skin test. Injection of tuberculin per se or a negative reaction did not induce similar changes. The described model seems useful for functional studies of ECs and lymphocytes in patients with contact dermatitis.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00417709

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