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  • 1
    ISSN: 1432-0533
    Keywords: Isolated Nerve Fibres ; Electron Microscopy ; Demyelination
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wird eine Technik zur Isolierung peripherer Nervenfasern durch Auffasern und nachfolgende licht-undd elektronenmikroskopische Untersuchung beschrieben. Diese Technik wurde zum Studium ungewöhnlich geschwollener Fasern angewandt, die proximal der Läsion bei durchschnittenen Nerven von Ratten beobachtet wurden. Diese Fasern wurden als das Ergebnis der Demyelinisation bereits remyelinisierter Segmente dargestellt.
    Notes: Summary A technique is described for isolating peripheral nerve fibres by teasing and subsequently examining them by light and electron microscopy. The technique was applied to the study of unusual swollen fibres observed central to the lesion in transected nerves in rats. These were shown to be the result of the demyelination of already remyelinated segments of the fibre.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 176 (1973), S. 225-243 
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Peripheral nerve fibers close to the sensory neurons of dorsal root ganglia displayed unusually thin myelin sheaths in relation to their axon diameter. Myelinated internodes along each fiber showed large differences in the numbers of myelin lamellae. These fibers are thought to represent spatial progression in degree of myelination as the axon egresses from the nonmyelinated glomerulus to the position of axonal bifurcation. This region is termed the initial complex of dorsal root ganglion cells. While the usual relationship between axon diameter and myelin sheath thickness is seen in the majority of dorsal root ganglion fibers, the fiber comprising each initial complex shows an atypical relationship in that the myelin sheath is unusually thin. Since the pattern of myelination in this small area is incongruous with previous reports attributing the control of myelin sheath thickness solely to axon diameter, the present findings indicate that other, unknown factors are operative in the control of myelination.
    Type of Medium: Electronic Resource
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