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  • 1
    Electronic Resource
    Electronic Resource
    Somatostatin and Alzheimer's disease: a hypothesis (1986)
    Springer
    Journal of neurology 233 (1986), S. 370-372 
    Details
    ISSN: 1432-1459
    Keywords: Alzheimer's disease ; Somatostatin ; Endocrine system ; Amyloid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Recent data suggest a disturbance of some brain somatostatin neurons in Alzheimer's disease. Moreover, some endocrine activities known to be regulated by somatostatin, such as growth hormone, thyroid-stimulating-hormone, somatomedins, as well as insulin and glucose metabolism, also seem to be affected in some patients. It is speculated that these changes are due to a global CNS and endocrine somatostatin defect in Alzheimer's disease and that the described endocrine imbalance may indirectly be responsible for at least part of the CNS pathology.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00313925
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